ANGIOMA SERPIGINOSUM, AUTOSOMAL DOMINANT

General Information (adopted from Orphanet):

Synonyms, Signs:
Number of Symptoms 10
OrphanetNr:
OMIM Id: 106050
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
Sporadic
[Omim]
Age of onset: Juvenile onset
[Omim]

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0000962) Hyperkeratosis 216 / 7739
2
(OMIM) Non-purpuric punctate and linear erythematous rash 2 / 7739
3
(OMIM) Lesions occur on the trunk, back, arms, legs, abdomen, buttocks 2 / 7739
4
(OMIM) Subepidermal capillary ectasia 2 / 7739
5
(OMIM) Inflammation is usually absent 2 / 7739
6
(OMIM) Nests of dilated and thick-walled capillaries in the dermal papillae 2 / 7739
7
(OMIM) Lesions often follow Blaschko lines 2 / 7739
8
(OMIM) Slit-like protrusion of capillary lumen into the endothelial lining 2 / 7739
9
(OMIM) Extensive cutaneous involvement rarely occurs 2 / 7739
10
(OMIM) Palms, soles, and oral mucosa are not involved 2 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Angioma serpiginosum is an uncommon benign skin disorder characterized by asymptomatic clusters of nonpurpuric punctate erythematous lesions. The rash is asymptomatic but may lead to cosmetic problems and can be treated by laser therapy. Women are most commonly ...
Clinical Description OMIM Angioma serpiginosum was first described by Jonathan Hutchinson (1889) in Plate IX of Vol. 1 of his Archives of Surgery. More common in females, the condition begins before puberty as pin-sized capillary puncta affecting any part of the ...