Morgagni-Stewart-Morel syndrome

General Information (adopted from Orphanet):

Synonyms, Signs: MORGAGNI-STEWART-MOREL SYNDROME
Hyperostosis frontalis interna
Number of Symptoms 10
OrphanetNr: 77296
OMIM Id: 144800
ICD-10: M85.2
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant
X-linked recessive
[Orphanet]
Age of onset: Adult
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Cranial malformation
 -Rare developmental defect during embryogenesis
Genetic cranial malformation
 -Rare genetic disease

Symptom Information: Sort by abundance 

1
 (HPO:0000858) Menstrual irregularities 42 / 7739
2
 (HPO:0004438) Hyperostosis frontalis interna 2 / 7739
3
 (HPO:0100829) Galactorrhea 7 / 7739
4
 (HPO:0000870) Prolactin excess 10 / 7739
5
 (HPO:0000819) Diabetes mellitus 131 / 7739
6
 (HPO:0001513) Obesity 172 / 7739
7
 (HPO:0000998) Hypertrichosis 52 / 7739
8
 (HPO:0003155) Elevated alkaline phosphatase 52 / 7739
9
 (HPO:0000006) Autosomal dominant inheritance 2518 / 7739
10
 (OMIM) Hyperphosphatasemia 2 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: