Primary cutaneous lymphoma
General Information (adopted from Orphanet):
| Synonyms, Signs: |
|
| Number of Symptoms | 28 |
| OrphanetNr: | 542 |
| OMIM Id: |
|
| ICD-10: |
C84 |
| UMLs: |
C1276146 C1302772 |
| MeSH: |
|
| MedDRA: |
10051708 |
| Snomed: |
28054005 400001003 419392005 |
Prevalence, inheritance and age of onset:
| Prevalence: | No data available. |
| Inheritance: |
|
| Age of onset: |
|
Disease classification (adopted from Orphanet):
| Parent Diseases: |
Primary organ-specific lymphoma
-Rare hematologic disease -Rare oncologic disease Rare skin tumor or hamartoma -Rare oncologic disease -Rare skin disease |
Symptom Information:
|
|
(HPO:0001357) | Plagiocephaly | Frequent [Orphanet] | 106 / 7739 | |||
|
|
(HPO:0000492) | Abnormality of the eyelid | Occasional [Orphanet] | 41 / 7739 | |||
|
|
(HPO:0002240) | Hepatomegaly | Frequent [Orphanet] | 467 / 7739 | |||
|
|
(HPO:0001744) | Splenomegaly | Frequent [Orphanet] | 337 / 7739 | |||
|
|
(HPO:0004325) | Decreased body weight | Frequent [Orphanet] | 492 / 7739 | |||
|
|
(HPO:0008065) | Aplasia/Hypoplasia of the skin | Very frequent [Orphanet] | 81 / 7739 | |||
|
|
(HPO:0001597) | Abnormality of the nail | Frequent [Orphanet] | 115 / 7739 | |||
|
|
(HPO:0200042) | Skin ulcer | Occasional [Orphanet] | 138 / 7739 | |||
|
|
(HPO:0000958) | Dry skin | Frequent [Orphanet] | 152 / 7739 | |||
|
|
(HPO:0200037) | Skin vesicle | Frequent [Orphanet] | 102 / 7739 | |||
|
|
(HPO:0001595) | Abnormality of the hair | Occasional [Orphanet] | 89 / 7739 | |||
|
|
(HPO:0000988) | Skin rash | Very frequent [Orphanet] | 98 / 7739 | |||
|
|
(HPO:0001596) | Alopecia | Frequent [Orphanet] | 162 / 7739 | |||
|
|
(HPO:0007400) | Irregular hyperpigmentation | Very frequent [Orphanet] | 72 / 7739 | |||
|
|
(HPO:0001031) | Subcutaneous lipoma | Very frequent [Orphanet] | 112 / 7739 | |||
|
|
(HPO:0001053) | Hypopigmented skin patches | Very frequent [Orphanet] | 80 / 7739 | |||
|
|
(HPO:0000989) | Pruritus | Frequent [Orphanet] | 111 / 7739 | |||
|
|
(HPO:0010783) | Erythema | Frequent [Orphanet] | 138 / 7739 | |||
|
|
(HPO:0000962) | Hyperkeratosis | Frequent [Orphanet] | 216 / 7739 | |||
|
|
(HPO:0001871) | Abnormality of blood and blood-forming tissues | Occasional [Orphanet] | 37 / 7739 | |||
|
|
(HPO:0002665) | Lymphoma | Very frequent [Orphanet] | 60 / 7739 | |||
|
|
(HPO:0004332) | Abnormality of lymphocytes | Occasional [Orphanet] | 12 / 7739 | |||
|
|
(HPO:0001945) | Fever | Frequent [Orphanet] | 218 / 7739 | |||
|
|
(HPO:0002716) | Lymphadenopathy | Frequent [Orphanet] | 129 / 7739 | |||
|
|
(HPO:0003549) | Abnormality of connective tissue | Occasional [Orphanet] | 22 / 7739 | |||
|
|
(MedDRA:10025421) | Macule | Frequent [Orphanet] | 55 / 7739 | |||
|
|
(OMIM) | Stiff skin | Very frequent [Orphanet] | 31 / 7739 | |||
|
|
(HPO:0030350) | Erythematous papule | Frequent [Orphanet] | 123 / 7739 |
Associated genes:
ClinVar (via SNiPA)
| Gene symbol | Variation | Clinical significance | Reference |
|---|