Cutaneous lupus erythematosus

General Information (adopted from Orphanet):

Synonyms, Signs:
Number of Symptoms 20
OrphanetNr: 535
OMIM Id:
ICD-10: L93
UMLs: C0024137
MeSH: D008178
MedDRA: 10056509
Snomed: 7119001

Prevalence, inheritance and age of onset:

Prevalence: 50 of 100 000 [Orphanet]
Inheritance: Multifactorial
[Orphanet]
Age of onset: All ages
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Autoimmune disease with skin involvement
 -Rare skin disease

Symptom Information: Sort by abundance 

1
 (HPO:0005059) Arthralgia/arthritis Very frequent [Orphanet] 141 / 7739
2
 (HPO:0100585) Telangiectasia of the skin Very frequent [Orphanet] 66 / 7739
3
 (HPO:0200042) Skin ulcer Very frequent [Orphanet] 138 / 7739
4
 (HPO:0000992) Cutaneous photosensitivity Occasional [Orphanet] 75 / 7739
5
 (HPO:0003765) Psoriasis Very frequent [Orphanet] 17 / 7739
6
 (HPO:0010783) Erythema Very frequent [Orphanet] 138 / 7739
7
 (HPO:0000988) Skin rash Very frequent [Orphanet] 98 / 7739
8
 (HPO:0000962) Hyperkeratosis Very frequent [Orphanet] 216 / 7739
9
 (HPO:0000989) Pruritus Very frequent [Orphanet] 111 / 7739
10
 (HPO:0011123) Inflammatory abnormality of the skin Very frequent [Orphanet] 10 / 7739
11
 (HPO:0007400) Irregular hyperpigmentation Very frequent [Orphanet] 72 / 7739
12
 (HPO:0200037) Skin vesicle Very frequent [Orphanet] 102 / 7739
13
 (HPO:0001063) Acrocyanosis Very frequent [Orphanet] 56 / 7739
14
 (HPO:0001031) Subcutaneous lipoma Very frequent [Orphanet] 112 / 7739
15
 (HPO:0000958) Dry skin Very frequent [Orphanet] 152 / 7739
16
 (HPO:0000969) Edema Very frequent [Orphanet] 117 / 7739
17
 (HPO:0012740) Papilloma Occasional [Orphanet] 17 / 7739
18
 (OMIM) Stiff skin Very frequent [Orphanet] 31 / 7739
19
 (MedDRA:10025421) Macule Very frequent [Orphanet] 55 / 7739
20
 (HPO:0030350) Erythematous papule Very frequent [Orphanet] 123 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: