Classical mycosis fungoides

General Information (adopted from Orphanet):

Synonyms, Signs: Mycosis fungoides, Alibert-Bazin type
Number of Symptoms 30
OrphanetNr: 2584
OMIM Id: 254400
ICD-10: C84.0
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Multifactorial
Not applicable
[Orphanet]
Age of onset: Adult
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Mycosis fungoides and variants
 -Rare hematologic disease
 -Rare oncologic disease
 -Rare skin disease

Symptom Information: Sort by abundance 

1
 (HPO:0000492) Abnormality of the eyelid Occasional [Orphanet] 41 / 7739
2
 (HPO:0002240) Hepatomegaly Occasional [Orphanet] 467 / 7739
3
 (HPO:0001744) Splenomegaly Occasional [Orphanet] 337 / 7739
4
 (HPO:0010783) Erythema Very frequent [Orphanet] 138 / 7739
5
 (HPO:0000988) Skin rash Very frequent [Orphanet] 98 / 7739
6
 (HPO:0000976) Eczematoid dermatitis 22 / 7739
7
 (HPO:0000962) Hyperkeratosis Occasional [Orphanet] 216 / 7739
8
 (HPO:0000958) Dry skin Very frequent [Orphanet] 152 / 7739
9
 (HPO:0000964) Eczema Very frequent [Orphanet] 81 / 7739
10
 (HPO:0000989) Pruritus Very frequent [Orphanet] 111 / 7739
11
 (HPO:0008069) Neoplasm of the skin Very frequent [Orphanet] 84 / 7739
12
 (HPO:0001053) Hypopigmented skin patches Frequent [Orphanet] 80 / 7739
13
 (HPO:0001596) Alopecia Frequent [Orphanet] 162 / 7739
14
 (HPO:0200035) Skin plaque 2 / 7739
15
 (HPO:0001047) Atopic dermatitis 20 / 7739
16
 (HPO:0001597) Abnormality of the nail Occasional [Orphanet] 115 / 7739
17
 (HPO:0200042) Skin ulcer Occasional [Orphanet] 138 / 7739
18
 (HPO:0007400) Irregular hyperpigmentation Frequent [Orphanet] 72 / 7739
19
 (HPO:0001029) Poikiloderma Frequent [Orphanet] 23 / 7739
20
 (HPO:0002665) Lymphoma Very frequent [Orphanet] 60 / 7739
21
 (HPO:0005561) Abnormality of bone marrow cell morphology Occasional [Orphanet] 11 / 7739
22
 (HPO:0004332) Abnormality of lymphocytes Very frequent [Orphanet] 12 / 7739
23
 (HPO:0000969) Edema Occasional [Orphanet] 117 / 7739
24
 (HPO:0002716) Lymphadenopathy Frequent [Orphanet] 129 / 7739
25
 (HPO:0030350) Erythematous papule Very frequent [Orphanet] 123 / 7739
26
 (OMIM) Stiff skin Very frequent [Orphanet] 31 / 7739
27
 (OMIM) Indurated skin plaques 1 / 7739
28
 (OMIM) Skin scaling 1 / 7739
29
 (OMIM) Malignant T-cell skin lymphoma 1 / 7739
30
 (MedDRA:10058675) Dermatitis psoriasiform 2 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Mycosis fungoides is a malignant T-cell lymphoma of the skin, first reported (and named) by Alibert (1835).