Search Results for "Fzd8" AND ARG_TAG:niche - 16 interactions found in 2 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information Experiment type
PubMed-ID
3,524
32830 Celsr2 increases_activity of Fzd8 Fmi regulates Fz8 distribution at the interface between HSCs and N-cadherin+osteoblasts in the niche.
32831 Fzd8 increases_activity of non-canonical Wnt signaling pathway
32836 HSC (Rho(lo)KSL) increases_expression of Fzd8
32848 HSC (CD34-CD135-KSL) increases_quantity of Fzd8
32850 HSC (LRC, CD135-KSL) increases_expression of Fzd8 in comparison to active HSC (non-LRC)
32856 HSC (CD34-CD135-CD150+) increases_expression of Fzd8
32940 Celsr2 interacts (colocalizes) with Fzd8 at the interface between HSC (LRC, CD135-KSL) cells and N-cad+-OBs in the trabecular bone region
22817897
3,537
32908 5-FU decreases_expression of Fzd8 in LT-HSC (CD34-CD135-KSL)
32938 Fzd8 increases_activity of repopulation >16 weeks of LT-HSC (CD34-CD135-KSL) in vivo
32942 Fzd8 increases_activity of quiescence of LT-HSC (CD34-CD135-KSL). Homing was not affected by knockout of Fmi or Fz8, nor did apoptosis increase in vivo
32947 Fzd8 interacts (colocalizes) with Calcium channel LTCC only in quiescent LRC HSCs in vivo
32949 Fzd8 decreases_quantity of Ca2+ in LT-HSCs in vivo
32953 Fzd8 decreases_activity of Nfat in quiescent LRC-HSCs, by inhibiting nuclear translocation of Nfat in vivo
32954 Fzd8 decreases_activity of canonical Wnt signaling pathway in quiescent LRC-HSCs, by inhibiting nuclear translocation of Nfat in vivo
33445 osteoblast (N-cadherin+) increases_quantity of Fzd8 in vivo
36498 Fzd8 decreases_quantity of Ca2+ in LT-HSCs
22817897
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