|
1,966
|
| 37237 |
sinusoidal endothelium (MECA-32+)
|
|
increases_quantity of
|
Plvap
|
|
|
|
15989959
|
|
2,569
|
| 24849 |
osteoblast (ALP+Thpo+)
|
|
increases_quantity of
|
Thpo
|
|
in vivo
|
| 24865 |
osteoblast (ALP+Thpo+)
|
|
increases_expression of
|
Thpo
|
|
in vivo
|
|
18371409
|
|
2,622
|
| 30671 |
Thpo
|
|
increases_activity of
|
non-cell autonomous activity
|
|
in vivo
|
|
18371409
|
|
2,628
|
| 24995 |
osteoblast (osteocalcin+)
|
|
increases_quantity of
|
Angpt1
|
|
in vivo
|
| 25002 |
osteoblast (osteocalcin+)
|
|
increases_expression of
|
Cdh11
|
in comparison to LT-HSC (Tie2+SP,KSL)
|
in vivo
|
| 25005 |
osteoblast (osteocalcin+)
|
|
increases_expression of
|
Cdh3
|
in comparison to LT-HSC (Tie2+SP,KSL)
|
in vivo
|
| 25848 |
osteoblast (osteocalcin+)
|
|
increases_quantity of
|
Bglap
|
|
in vivo
|
| 28999 |
osteoblast (osteocalcin+)
|
|
increases_expression of
|
Cdh2
|
in comparison to LT-HSC (Tie2+SP,KSL)
|
|
| 30670 |
Angpt1
|
|
increases_activity of
|
non-cell autonomous activity
|
|
|
|
15260986
|
|
2,756
|
| 25502 |
SNO cell (N-cadherin+CD45-)
|
|
increases_expression of
|
Bmpr1a
|
but Bmpr1a is not expressed in HSCs
|
in vivo
|
| 25507 |
SNO cell (N-cadherin+CD45-)
|
|
increases_quantity of
|
Cdh2
|
|
in vivo
|
| 30672 |
Bmpr1a
|
|
increases_activity of
|
non-cell autonomous activity
|
|
in vivo
|
|
14574412
|
|
2,761
|
| 25583 |
CAR cell
|
|
increases_expression of
|
Kitl
|
|
in vivo
|
| 25584 |
CAR cell
|
|
increases_expression of
|
Cxcl12
|
|
in vivo
|
| 25585 |
CAR cell
|
|
increases_expression of
|
Cebpa
|
|
in vivo
|
| 25586 |
CAR cell
|
|
increases_expression of
|
Pparg
|
|
in vivo
|
| 25589 |
CAR cell
|
|
increases_expression of
|
Runx2
|
|
in vivo
|
| 25590 |
CAR cell
|
|
increases_expression of
|
Sp7
|
|
in vivo
|
| 25593 |
CAR cell
|
|
decreases_expression of
|
Col1a1
|
|
in vivo
|
| 25594 |
CAR cell
|
|
decreases_expression of
|
Bglap
|
|
in vivo
|
| 25598 |
CAR cell
|
|
increases_expression of
|
Bmpr1a
|
|
in vivo
|
| 25600 |
CAR cell
|
|
increases_expression of
|
Pth1r
|
|
in vivo
|
| 37244 |
CAR cell
|
|
increases_quantity of
|
Vcam1
|
|
|
| 37245 |
CAR cell
|
|
increases_quantity of
|
Cd44
|
|
|
| 37246 |
CAR cell
|
|
increases_quantity of
|
Itgav
|
|
|
| 37247 |
CAR cell
|
|
increases_quantity of
|
Pdgfra
|
|
|
| 37248 |
CAR cell
|
|
increases_quantity of
|
Pdgfrb
|
|
|
|
20850355
|
|
2,766
|
| 25648 |
CAR cell
|
|
increases_quantity of
|
Cxcl12
|
|
in vivo
|
| 25665 |
CAR cell
|
|
increases_quantity of
|
Jag1
|
|
in vivo
|
| 30675 |
Jag1
|
|
increases_activity of
|
non-cell autonomous activity
|
|
in vivo
|
|
17174120
|
|
2,819
|
| 25981 |
osteoblast (osteopontin+)
|
|
increases_quantity of
|
Jag1
|
|
|
| 28805 |
osteoblast (osteopontin+)
|
|
increases_expression of
|
Pth1r
|
|
|
| 30677 |
Pth1r
|
|
increases_activity of
|
non-cell autonomous activity
|
|
|
|
14574413
|
|
2,824
|
| 26081 |
osteoblast (osteopontin+)
|
|
increases_quantity of
|
Il6
|
in the transgenic stroma; via PPR induction
|
|
| 26082 |
osteoblast (osteopontin+)
|
|
increases_quantity of
|
Kitl
|
in the transgenic stroma; via PPR induction
|
|
| 26083 |
osteoblast (osteopontin+)
|
|
increases_quantity of
|
Cxcl12
|
in the transgenic stroma; via PPR induction
|
|
| 26690 |
osteoblast (osteopontin+)
|
|
increases_quantity of
|
Spp1
|
|
|
|
14574413
|
|
2,830
|
| 26133 |
trabecular bone (Col2.3-GFP+)
|
|
increases_expression of
|
Cxcl12
|
in response to irradiation
|
|
| 26138 |
osteoblast (N-cadherin+)
|
|
increases_quantity of
|
Cdh2
|
|
|
|
19052548
|
|
2,834
|
| 26310 |
osteoblast
|
|
increases_expression of
|
Dkk1
|
if Dkk1 is under the control of the osteoblast-specific Col1alpha promoter
|
in vivo
|
| 30678 |
Dkk1
|
|
increases_activity of
|
non-cell autonomous activity
|
|
in vivo
|
|
18371452
|
|
2,856
|
| 26336 |
osteoblast-enriched cell (Alcam+Sca1-)
|
|
increases_expression of
|
Runx2
|
in comparison to Alcam-Sca1+ cells
|
|
| 26343 |
endosteal cell (Alcam-Sca1-)
|
|
increases_expression of
|
Runx2
|
in comparison to Alcam-Sca1+ cells
|
|
| 26344 |
primary MSC-enriched cell (Alcam-Sca1+)
|
|
decreases_expression of
|
Runx2
|
in comparison to Alcam-Sca1-/Alcam+Sca1- cells
|
|
| 26345 |
endosteal cell (Alcam-Sca1-)
|
|
increases_expression of
|
Spp1
|
in comparison to Alcam-Sca1+/Alcam+Sca1- cells
|
|
| 26346 |
osteoblast-enriched cell (Alcam+Sca1-)
|
|
increases_expression of
|
Bglap
|
in comparison to Alcam-Sca1-/Alcam-Sca1+ cells
|
|
| 26348 |
primary MSC-enriched cell (Alcam-Sca1+)
|
|
decreases_expression of
|
Spp1
|
in comparison to Alcam+Sca1-/Alcam-Sca1- cells
|
|
| 26351 |
primary MSC-enriched cell (Alcam-Sca1+)
|
|
increases_expression of
|
Eng
|
|
|
| 26353 |
osteoblast-enriched cell (Alcam+Sca1-)
|
|
decreases_expression of
|
Eng
|
|
|
| 26358 |
osteoblast-enriched cell (Alcam+Sca1-)
|
|
increases_expression of
|
Alcam
|
|
|
| 26359 |
osteoblast-enriched cell (Alcam+Sca1-)
|
|
increases_expression of
|
Cdh2
|
|
|
| 26360 |
osteoblast-enriched cell (Alcam+Sca1-)
|
|
increases_expression of
|
Ncam1
|
|
|
| 26361 |
osteoblast-enriched cell (Alcam+Sca1-)
|
|
increases_expression of
|
Cdh15
|
|
|
| 26362 |
osteoblast-enriched cell (Alcam+Sca1-)
|
|
increases_expression of
|
Cadm1
|
|
|
| 26363 |
osteoblast-enriched cell (Alcam+Sca1-)
|
|
increases_expression of
|
Jam2
|
|
|
| 26364 |
osteoblast-enriched cell (Alcam+Sca1-)
|
|
increases_expression of
|
Cdh11
|
|
|
| 26365 |
osteoblast-enriched cell (Alcam+Sca1-)
|
|
increases_expression of
|
Col1a1
|
|
|
| 26366 |
osteoblast-enriched cell (Alcam+Sca1-)
|
|
increases_expression of
|
Timp3
|
|
|
| 26367 |
osteoblast-enriched cell (Alcam+Sca1-)
|
|
increases_expression of
|
Bmp2
|
|
|
| 26368 |
primary MSC-enriched cell (Alcam-Sca1+)
|
|
increases_expression of
|
Angpt1
|
|
|
| 26369 |
primary MSC-enriched cell (Alcam-Sca1+)
|
|
increases_expression of
|
Nov
|
|
|
| 26370 |
primary MSC-enriched cell (Alcam-Sca1+)
|
|
increases_expression of
|
Vcam1
|
|
|
| 26372 |
primary MSC-enriched cell (Alcam-Sca1+)
|
|
increases_expression of
|
Bmp4
|
|
|
| 26373 |
primary MSC-enriched cell (Alcam-Sca1+)
|
|
increases_expression of
|
Flt3l
|
|
|
| 26374 |
primary MSC-enriched cell (Alcam-Sca1+)
|
|
increases_expression of
|
Cxcl12
|
|
|
| 26375 |
primary MSC-enriched cell (Alcam-Sca1+)
|
|
increases_expression of
|
Kitl
|
|
|
| 26376 |
osteoblast-enriched cell (Alcam+Sca1-)
|
|
increases_expression of
|
Nanog
|
|
|
| 26377 |
osteoblast-enriched cell (Alcam+Sca1-)
|
|
increases_expression of
|
Thpo
|
|
|
|
20472830
|
|
2,858
|
| 26386 |
osteocyte
|
|
increases_expression of
|
Bmp4
|
|
in vivo
|
| 26402 |
osteoblast
|
|
increases_expression of
|
Bmp4
|
|
in vivo
|
| 26403 |
endothelial cell
|
|
increases_expression of
|
Bmp4
|
|
in vivo
|
| 30679 |
Bmp4
|
|
increases_activity of
|
non-cell autonomous activity
|
|
in vivo
|
|
19759357
|
|
2,862
|
| 26413 |
osteoblast (N-cadherin+)
|
|
increases_expression of
|
Ebf2
|
|
in vivo
|
| 26443 |
Ebf2
|
|
increases_expression of
|
Prl2c2
|
in osteoblasts
|
|
| 26445 |
Ebf2
|
|
decreases_expression of
|
Sfrp1
|
in osteoblasts
|
|
| 26446 |
Ebf2
|
|
decreases_expression of
|
Sfrp2
|
in osteoblasts
|
|
| 26482 |
Ebf2
|
|
increases_expression of
|
Il2rg
|
in osteoblasts
|
|
| 26483 |
Ebf2
|
|
increases_expression of
|
Ngfr
|
in osteoblasts
|
|
| 26484 |
Ebf2
|
|
increases_expression of
|
Aif1
|
in osteoblasts
|
|
| 26485 |
Ebf2
|
|
increases_expression of
|
Opg
|
in osteoblasts
|
|
| 26486 |
Ebf2
|
|
decreases_expression of
|
Agtr2
|
in osteoblasts
|
|
| 26487 |
Ebf2
|
|
decreases_expression of
|
Adipoq
|
in osteoblasts
|
|
| 26488 |
Ebf2
|
|
decreases_expression of
|
Thy1
|
in osteoblasts
|
|
| 26489 |
Ebf2
|
|
decreases_expression of
|
Cxcl14
|
in osteoblasts
|
|
| 28079 |
osteoblast (Ebf2+)
|
|
increases_expression of
|
Prl2c2
|
in response to extrinsic factor Ebf2. Expression is decreased in osteoblasts from Ebf2-/- mice.
|
|
| 28080 |
osteoblast (Ebf2+)
|
|
decreases_expression of
|
Sfrp1
|
in response to extrinsic factor Ebf2. Expression is increased in osteoblasts from Ebf2-/- mice.
|
|
| 28081 |
osteoblast (Ebf2+)
|
|
decreases_expression of
|
Sfrp2
|
in response to extrinsic factor Ebf2. Expression is increased in osteoblasts from Ebf2-/- mice.
|
|
| 28083 |
osteoblast (Ebf2+)
|
|
increases_expression of
|
Il2rg
|
in response to extrinsic factor Ebf2. Expression is decreased in osteoblasts from Ebf2-/- mice.
|
|
| 28084 |
osteoblast (Ebf2+)
|
|
increases_expression of
|
Ngfr
|
in response to extrinsic factor Ebf2. Expression is decreased in osteoblasts from Ebf2-/- mice.
|
|
| 28085 |
osteoblast (Ebf2+)
|
|
increases_expression of
|
Aif1
|
in response to extrinsic factor Ebf2. Expression is decreased in osteoblasts from Ebf2-/- mice.
|
|
| 28086 |
osteoblast (Ebf2+)
|
|
increases_expression of
|
Opg
|
in response to extrinsic factor Ebf2. Expression is decreased in osteoblasts from Ebf2-/- mice.
|
|
| 28087 |
osteoblast (Ebf2+)
|
|
decreases_expression of
|
Agtr2
|
in response to extrinsic factor Ebf2. Expression is increased in osteoblasts from Ebf2-/- mice.
|
|
| 28088 |
osteoblast (Ebf2+)
|
|
decreases_expression of
|
Adipoq
|
in response to extrinsic factor Ebf2. Expression is increased in osteoblasts from Ebf2-/- mice.
|
|
| 28089 |
osteoblast (Ebf2+)
|
|
decreases_expression of
|
Thy1
|
in response to extrinsic factor Ebf2. Expression is increased in osteoblasts from Ebf2-/- mice.
|
|
| 30020 |
osteoblast (Ebf2+)
|
|
increases_expression of
|
Runx2
|
|
|
| 30022 |
osteoblast (Ebf2+)
|
|
decreases_expression of
|
Bglap
|
|
in vivo
|
| 30024 |
osteoblast (N-cadherin+)
|
|
increases_quantity of
|
Ebf2
|
|
in vivo
|
| 30680 |
Ebf2
|
|
increases_activity of
|
non-cell autonomous activity
|
|
in vivo
|
| 32512 |
osteoblast (Ebf2+)
|
|
increases_quantity of
|
Ebf2
|
|
in vivo
|
|
20887955
|
|
2,878
|
| 26502 |
osteoblast
|
|
increases_expression of
|
Wif1
|
|
in vivo
|
| 26521 |
osteoblast
|
|
increases_expression of
|
Jag1
|
in Wif1-overexpressing osteoblasts. Expression is down-regulated after 5-FU-treatment
|
in vivo
|
| 26522 |
osteoblast
|
|
increases_expression of
|
Cdh2
|
in Wif1-overexpressing osteoblasts. Expression is down-regulated after 5-FU-treatment
|
in vivo
|
| 26523 |
osteoblast
|
|
increases_expression of
|
Bmp4
|
in Wif1-overexpressing osteoblasts. Expression is down-regulated after 5-FU-treatment
|
in vivo
|
| 26524 |
osteoblast
|
|
increases_expression of
|
Shh
|
in Wif1-overexpressing osteoblasts. Expression is down-regulated after 5-FU-treatment
|
in vivo
|
| 26541 |
osteoblast
|
|
increases_expression of
|
Cxcl12
|
in Wif1-overexpressing osteoblasts. Expression is not influenced by 5-FU treatment
|
in vivo
|
| 30668 |
Wif1
|
|
increases_activity of
|
non-cell autonomous activity
|
|
in vivo
|
|
21652676
|
|
2,895
|
| 26590 |
osteoblast (osteopontin+)
|
|
increases_quantity of
|
Spp1
|
|
in vivo
|
| 30676 |
Spp1
|
|
increases_activity of
|
non-cell autonomous activity
|
|
in vivo
|
|
15845900
|
|
2,899
|
| 26605 |
endosteum (trOPN+)
|
|
increases_quantity of
|
Spp1
|
The Thrombin-cleaved truncated form of Opn is abundant in the endosteum.
|
|
|
19417209
|
|
2,923
|
| 26775 |
vascular endothelial cell (PECAM1+)
|
|
increases_quantity of
|
Vcam1
|
which is a major receptor of HSC (CD34-KSL)
|
in vivo
|
| 26778 |
Reactive oxygen species
|
|
increases_quantity of
|
Vcam1
|
in vascular endothelial cell (PECAM1)
|
in vivo
|
|
19797522
|
|
2,940
|
| 26848 |
endosteum
|
|
increases_quantity of
|
Ca2+
|
|
|
| 30138 |
osteoclast
|
|
increases_quantity of
|
Ca2+
|
|
|
|
16382241
|
|
2,944
|
| 26851 |
response to hypoxia
|
|
decreases_quantity of
|
Reactive oxygen species
|
|
|
|
21670467
|
|
3,117
|
| 28697 |
osteoblastic bone-lining cell (CD45-Ter119-CD31-)
|
|
increases_expression of
|
Cxcl12
|
in RelB/Nfkb2 double knockout mice expression is reduced compared to WT mice
|
|
| 28701 |
osteoblastic bone-lining cell (CD45-Ter119-CD31-)
|
|
increases_expression of
|
Thpo
|
in RelB/Nfkb2 double knockout mice expression is reduced compared to WT mice
|
|
| 28702 |
osteoblastic bone-lining cell (CD45-Ter119-CD31-)
|
|
increases_expression of
|
Kitl
|
in RelB/Nfkb2 double knockout mice expression is reduced compared to WT mice
|
|
| 28704 |
osteoblastic bone-lining cell (CD45-Ter119-CD31-)
|
|
increases_expression of
|
Spp1
|
in RelB/Nfkb2 double knockout mice expression is reduced compared to WT mice
|
|
| 28705 |
osteoblastic bone-lining cell (CD45-Ter119-CD31-)
|
|
increases_expression of
|
Bglap
|
in RelB/Nfkb2 double knockout mice expression is increased compared to WT mice
|
|
|
22290873
|
|
3,132
|
| 28863 |
SNO cell (N-cadherin+CD45-)
|
|
increases_quantity of
|
Cdh2
|
in c-Myc-deficient mice
|
in vivo
|
|
15545632
|
|
3,142
|
| 30673 |
Kitl
|
|
increases_activity of
|
non-cell autonomous activity
|
|
|
|
14662336
|
|
3,160
|
| 29075 |
endothelioma cell line
|
|
increases_expression of
|
Vcam1
|
Expression is reduced in a co-culture with Wnt3a-expressing OP9 cells
|
|
|
18951693
|
|
3,163
|
| 32746 |
Vcam1
|
|
increases_activity of
|
non-cell autonomous activity
|
|
in vivo
|
|
7568190
|
|
3,182
|
| 29181 |
MSC (Nes+)
|
|
increases_quantity of
|
Nes
|
in contrast to vascular endothelial cells
|
|
| 29203 |
MSC (Nes+)
|
|
increases_expression of
|
Adrb3
|
in comparison to unlabeled MSC (Nes-GFP-) cells
|
|
| 29207 |
MSC (Nes+)
|
|
increases_expression of
|
Cxcl12
|
in contrast to osteoblasts or osteoclasts
|
|
| 29209 |
MSC (Nes+)
|
|
increases_expression of
|
Angpt1
|
in comparison to unlabeled MSC (Nes-GFP-) cells or osteoblasts
|
|
| 29220 |
MSC (Nes+)
|
|
increases_expression of
|
Cxcl12
|
in comparison to unlabeled MSC (Nes-GFP-) cells. Expression is down-regulated after addition of G-CSF.
|
in vivo
|
| 29221 |
MSC (Nes+)
|
|
increases_expression of
|
Kitl
|
in comparison to unlabeled MSC (Nes-GFP-) cells. Expression is down-regulated after addition of G-CSF.
|
in vivo
|
| 29222 |
MSC (Nes+)
|
|
increases_expression of
|
Angpt1
|
in comparison to unlabeled MSC (Nes-GFP-) cells. Expression is down-regulated after addition of G-CSF.
|
in vivo
|
| 29223 |
MSC (Nes+)
|
|
increases_expression of
|
Il7
|
in comparison to unlabeled MSC (Nes-GFP-) cells. Expression is down-regulated after addition of G-CSF.
|
in vivo
|
| 29224 |
MSC (Nes+)
|
|
increases_expression of
|
Vcam1
|
in comparison to unlabeled MSC (Nes-GFP-) cells. Expression is down-regulated after addition of G-CSF.
|
in vivo
|
| 29225 |
MSC (Nes+)
|
|
increases_expression of
|
Spp1
|
in comparison to unlabeled MSC (Nes-GFP-) cells
|
in vivo
|
| 35326 |
MSC (Nes+)
|
|
increases_expression of
|
Gja1
|
in comparison to unlabeled MSC (Nes-GFP-) cells
|
in vivo
|
| 35327 |
MSC (Nes+)
|
|
increases_expression of
|
Gjc1
|
in comparison to unlabeled MSC (Nes-GFP-) cells
|
in vivo
|
|
20703299
|
|
3,203
|
| 29481 |
osteoblast (ALP)
|
|
increases_quantity of
|
Vcam1
|
Vcam1 expression depends on beta-catenin. It is reduced in beta-catenin deficient mice
|
|
| 29482 |
sinusoidal endothelium (MECA-32+)
|
|
increases_quantity of
|
Vcam1
|
Vcam1 expression depends on beta-catenin. It is reduced in beta-catenin deficient mice
|
|
|
19415781
|
|
3,322
|
| 30674 |
Cxcl12
|
|
increases_activity of
|
non-cell autonomous activity
|
|
|
|
18378795
|
|
3,328
|
| 30620 |
osteoblast (osteocalcin+)
|
|
increases_quantity of
|
Slit2
|
Expression is induced in response to myelosuppresive stress (5-FU)
|
in vivo
|
| 30622 |
Slit2
|
|
increases_activity of
|
non-cell autonomous activity
|
|
in vivo
|
|
18927479
|
|
3,337
|
| 30666 |
endothelial cell
|
|
increases_quantity of
|
Hyaluronate
|
|
in vitro
|
| 30667 |
Hyaluronate
|
|
increases_activity of
|
non-cell autonomous activity
|
|
in vitro
|
|
22654110
|
HSC