HSCGeneral Information:
| Id: | 3,680 (click here to show other Interactions for entry) |
| Mus musculus | |
| C57BL/6 (B6-Ly5.2)/(B6-Ly5.1); Mx-1-Cre, 2 month-old; Tgfbr2flox/-Rag2-/- mice | |
| Reference: | Yamazaki S et al.(2011) Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche Cell 147: 1146-1158 [PMID: 22118468] |
Interaction Information:
| Comment | Glial cells are responsible for the maintenance of HSC hibernation in BM by regulating the process by which latent TGF-beta is activated. [Method: CD34-KSL cells after denervation of sympathetic nerves, BrdU-labeling] |
|
Formal Description Interaction-ID: 35309 |
tissue/cell line non-myelinated Schwann cell (GFAP+) increases_activity of process |