General Information:

Id: 3,363 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Hypothyroidism
Insulin resistance
Rattus norvegicus
pre-diabetic Zucker diabetic fatty (ZDF) rats
article
Reference: Yi SS et al.(2010) Effects of hypothyroidism on cell proliferation and neuroblasts in the hippocampal dentate gyrus in a rat model of type 2 diabetes Anat Cell Biol 43: 185-193 [PMID: 21212858]

Interaction Information:

Comment Methimazole (methi) treatment in the ZDF rats (ZDF-methi rats) significantly decreased corticosterone levels.
Formal Description
Interaction-ID: 30870

drug/chemical compound

Thiamazole

decreases_activity of

gene/protein

TPO

in thyroid gland
Drugbank entries Show/Hide entries for TPO