|
1
|
(HPO:0000089)
|
Renal hypoplasia |
|
|
|
|
78 / 7739
|
|
2
|
(HPO:0000092)
|
Tubular atrophy |
|
|
|
|
28 / 7739
|
|
3
|
(HPO:0000096)
|
Glomerulosclerosis |
|
|
|
|
11 / 7739
|
|
4
|
(HPO:0000127)
|
Renal salt wasting |
|
|
|
|
21 / 7739
|
|
5
|
(HPO:0000822)
|
Hypertension |
|
|
|
|
224 / 7739
|
|
6
|
(HPO:0001903)
|
Anemia |
|
|
|
|
289 / 7739
|
|
7
|
(HPO:0001970)
|
Tubulointerstitial nephritis |
|
|
|
|
27 / 7739
|
|
8
|
(HPO:0001997)
|
Gout |
|
|
|
|
18 / 7739
|
|
9
|
(HPO:0002120)
|
Cerebral cortical atrophy |
|
|
|
|
187 / 7739
|
|
10
|
(HPO:0003259)
|
Elevated serum creatinine |
|
|
|
|
31 / 7739
|
|
11
|
(HPO:0004732)
|
Impaired renal uric acid clearance |
|
|
|
|
2 / 7739
|
|
12
|
(HPO:0005576)
|
Tubulointerstitial fibrosis |
|
|
|
|
32 / 7739
|
|
13
|
(HPO:0005583)
|
Tubular basement membrane disintegration |
|
|
|
|
18 / 7739
|
|
14
|
(HPO:0012213)
|
Decreased glomerular filtration rate |
|
|
|
|
21 / 7739
|
|
15
|
(OMIM)
|
Hypotension may occur late in disease due to salt wasting |
|
|
|
|
1 / 7739
|
|
16
|
(HPO:0012211)
|
Abnormal renal physiology |
|
|
|
|
23 / 7739
|
|
17
|
(OMIM)
|
Interstitial inflammation |
|
|
|
|
1 / 7739
|
|
18
|
(OMIM)
|
Renal biopsy shows medullary cysts |
|
|
|
|
1 / 7739
|
|
19
|
(OMIM)
|
Corticomedullary cysts |
|
|
|
|
4 / 7739
|
|
20
|
(OMIM)
|
Cysts may be absent in over 50% of patients |
|
|
|
|
1 / 7739
|
|
21
|
(OMIM)
|
Progression to end stage renal failure in late adulthood (fifth to seventh decade) |
|
|
|
|
1 / 7739
|
|
22
|
(HPO:0002149)
|
Hyperuricemia |
|
|
|
|
37 / 7739
|