|
1
|
(HPO:0000710)
|
Hyperorality |
|
|
|
|
6 / 7739
|
|
2
|
(HPO:0000733)
|
Stereotypy |
|
|
|
|
58 / 7739
|
|
3
|
(HPO:0000734)
|
Disinhibition |
|
|
|
|
13 / 7739
|
|
4
|
(HPO:0000737)
|
Irritability |
|
|
|
|
93 / 7739
|
|
5
|
(HPO:0000741)
|
Apathy |
|
|
|
|
42 / 7739
|
|
6
|
(HPO:0000748)
|
Inappropriate laughter |
|
|
|
|
5 / 7739
|
|
7
|
(HPO:0000751)
|
Personality changes |
|
|
|
|
33 / 7739
|
|
8
|
(HPO:0002145)
|
Frontotemporal dementia |
|
|
|
|
14 / 7739
|
|
9
|
(HPO:0002463)
|
Language impairment |
|
|
|
|
15 / 7739
|
|
10
|
(HPO:0002476)
|
Primitive reflex |
|
|
|
|
9 / 7739
|
|
11
|
(HPO:0002529)
|
Neuronal loss in central nervous system |
|
|
|
|
37 / 7739
|
|
12
|
(HPO:0002591)
|
Polyphagia |
|
|
|
|
25 / 7739
|
|
13
|
(HPO:0010529)
|
Echolalia |
|
|
|
|
20 / 7739
|
|
14
|
(OMIM)
|
Frontotemporal lobar atrophy with 'knife-edge' distinction |
|
|
|
|
1 / 7739
|
|
15
|
(OMIM)
|
Atrophy may be more severe in the left hemisphere |
|
|
|
|
1 / 7739
|
|
16
|
(OMIM)
|
Argyrophilic hyperphosphorylated tau-positive inclusions (Pick bodies) |
|
|
|
|
1 / 7739
|
|
17
|
(OMIM)
|
Swollen achromatic cells (Pick cells) |
|
|
|
|
1 / 7739
|
|
18
|
(OMIM)
|
Pick bodies found in neocortical layers, granule cells of the dentate gyrus, and throughout the hippocampus |
|
|
|
|
1 / 7739
|
|
19
|
(OMIM)
|
Astrogliosis |
|
|
|
|
3 / 7739
|
|
20
|
(HPO:0000745)
|
Diminished motivation |
|
|
|
|
2 / 7739
|
|
21
|
(OMIM)
|
Emotional blunting |
|
|
|
|
1 / 7739
|
|
22
|
(MedDRA:10034703)
|
Perseveration |
|
|
|
|
3 / 7739
|