1
|
(HPO:0000012)
|
Urinary urgency |
|
|
|
|
35 / 7739
|
2
|
(HPO:0000298)
|
Mask-like facies |
|
|
|
|
44 / 7739
|
3
|
(HPO:0000716)
|
Depression |
|
|
|
|
99 / 7739
|
4
|
(HPO:0000726)
|
Dementia |
|
|
|
|
131 / 7739
|
5
|
(HPO:0000738)
|
Hallucinations |
occasional [HPO:skoehler]
|
|
|
|
60 / 7739
|
6
|
(HPO:0000751)
|
Personality changes |
|
|
|
|
33 / 7739
|
7
|
(HPO:0001260)
|
Dysarthria |
|
|
|
|
329 / 7739
|
8
|
(HPO:0001300)
|
Parkinsonism |
|
|
|
|
75 / 7739
|
9
|
(HPO:0001332)
|
Dystonia |
|
|
|
|
197 / 7739
|
10
|
(HPO:0001621)
|
Weak voice |
|
|
|
|
5 / 7739
|
11
|
(HPO:0002015)
|
Dysphagia |
|
|
|
|
301 / 7739
|
12
|
(HPO:0002019)
|
Constipation |
|
|
|
|
194 / 7739
|
13
|
(HPO:0002063)
|
Rigidity |
|
|
|
|
92 / 7739
|
14
|
(HPO:0002067)
|
Bradykinesia |
|
|
|
|
62 / 7739
|
15
|
(HPO:0002172)
|
Postural instability |
|
|
|
|
22 / 7739
|
16
|
(HPO:0002322)
|
Resting tremor |
|
|
|
|
14 / 7739
|
17
|
(HPO:0002360)
|
Sleep disturbance |
|
|
|
|
113 / 7739
|
18
|
(HPO:0002459)
|
Dysautonomia |
occasional [HPO:skoehler]
|
|
|
|
34 / 7739
|
19
|
(HPO:0002529)
|
Neuronal loss in central nervous system |
|
|
|
|
37 / 7739
|
20
|
(HPO:0007311)
|
Short stepped shuffling gait |
|
|
|
|
3 / 7739
|
21
|
(HPO:0011960)
|
Substantia nigra gliosis |
|
|
|
|
4 / 7739
|
22
|
(HPO:0100315)
|
Lewy bodies |
|
|
|
|
5 / 7739
|
23
|
(MedDRA:10026863)
|
Masked facies |
|
|
|
|
8 / 7739
|
24
|
(OMIM)
|
Decreased sense of smell |
|
|
|
|
1 / 7739
|
25
|
(MedDRA:10057333)
|
Micrographia |
|
|
|
|
3 / 7739
|
26
|
(HPO:0001288)
|
Gait disturbance |
|
|
|
|
318 / 7739
|
27
|
(HPO:0002362)
|
Shuffling gait |
|
|
|
|
13 / 7739
|
28
|
(OMIM)
|
Monotonous speech |
|
|
|
|
1 / 7739
|
29
|
(OMIM)
|
Dysautonomia may occur |
|
|
|
|
1 / 7739
|
30
|
(OMIM)
|
Visual hallucinations may occur |
|
|
|
|
1 / 7739
|
31
|
(OMIM)
|
Dementia may occur |
|
|
|
|
1 / 7739
|
32
|
(OMIM)
|
Neuronal loss and gliosis in the substantia nigra pars compacta |
|
|
|
|
2 / 7739
|
33
|
(OMIM)
|
Loss of dopaminergic neurons |
|
|
|
|
1 / 7739
|
34
|
(OMIM)
|
Intracellular Lewy bodies |
|
|
|
|
1 / 7739
|
35
|
(OMIM)
|
Aggregation of SNCA-immunopositive inclusions |
|
|
|
|
1 / 7739
|
36
|
(HPO:0003587)
|
Insidious onset |
|
|
|
|
11 / 7739
|
37
|
(HPO:0003676)
|
Progressive disorder |
|
|
|
|
148 / 7739
|