|
1
|
(MedDRA:10051177)
|
Electrocardiogram Q wave abnormal |
Occasional [IBIS]
|
29% (n=69)
|
9631872
|
IBIS
|
6 / 7739
|
|
2
|
(MedDRA:10050380)
|
Electrocardiogram T wave abnormal |
Occasional [IBIS]
|
29% (n=69)
|
9631872
|
IBIS
|
5 / 7739
|
|
3
|
(HPO:0001712)
|
Left ventricular hypertrophy |
Occasional [IBIS]
|
25% (n=69)
|
9631872, 9562578
|
IBIS
|
76 / 7739
|
|
4
|
(MedDRA:10057624)
|
QRS axis abnormal |
Occasional [IBIS]
|
22% (n=69)
|
9631872
|
IBIS
|
2 / 7739
|
|
5
|
(HPO:0001645)
|
Sudden cardiac death |
Occasional [IBIS]
|
12% (n=281)
|
9562578
|
IBIS
|
84 / 7739
|
|
6
|
(HPO:0012248)
|
Prolonged PR interval |
Rare [IBIS]
|
3% (n=69)
|
9631872
|
IBIS
|
6 / 7739
|
|
7
|
(HPO:0001639)
|
Hypertrophic cardiomyopathy |
|
|
9631872
|
IBIS
|
137 / 7739
|
|
8
|
(HPO:0002094)
|
Dyspnea |
|
|
9562578
|
IBIS
|
132 / 7739
|
|
9
|
(HPO:0001681)
|
Angina pectoris |
|
|
9562578
|
IBIS
|
22 / 7739
|
|
10
|
(HPO:0001279)
|
Syncope |
|
|
9562578
|
IBIS
|
94 / 7739
|
|
11
|
(HPO:0003115)
|
Abnormal EKG |
|
|
9631872
|
IBIS
|
44 / 7739
|
|
12
|
(HPO:0001635)
|
Congestive heart failure |
|
|
17937428
|
IBIS
|
232 / 7739
|
|
13
|
(HPO:0003116)
|
Abnormal echocardiogram |
|
|
17937428
|
IBIS
|
33 / 7739
|
|
14
|
(HPO:0001716)
|
Wolff-Parkinson-White syndrome |
|
|
9241277
|
IBIS
|
21 / 7739
|
|
15
|
(OMIM)
|
Ventricular preexcitation, Wolff-Parkinson-White (in some patients) |
|
|
9241277
|
IBIS
|
1 / 7739
|
|
16
|
(HPO:0100749)
|
Chest pain |
|
|
23840593
|
IBIS
|
92 / 7739
|
|
17
|
(OMIM)
|
Interventricular septal hypertrophy (1 patient) |
|
|
23840593
|
IBIS
|
3 / 7739
|
|
18
|
(MedDRA:10057576)
|
Cardiac septal hypertrophy |
|
|
23840593
|
IBIS
|
4 / 7739
|
|
19
|
(HPO:0012664)
|
Reduced ejection fraction |
|
|
23840593
|
IBIS
|
32 / 7739
|
|
20
|
(MedDRA:10050469)
|
Holt-Oram syndrome |
|
|
7623431
|
IBIS
|
1 / 7739
|
|
21
|
(HPO:0001670)
|
Asymmetric septal hypertrophy |
|
|
17655857
|
IBIS
|
19 / 7739
|
|
22
|
(HPO:0004756)
|
Ventricular tachycardia |
|
|
25740977
|
IBIS
|
55 / 7739
|