|
1
|
(HPO:0009830)
|
Peripheral neuropathy |
Frequent [Orphanet]
|
|
|
|
206 / 7739
|
|
2
|
(HPO:0003326)
|
Myalgia |
Frequent [Orphanet]
|
|
|
|
143 / 7739
|
|
3
|
(HPO:0200042)
|
Skin ulcer |
Very frequent [Orphanet]
|
|
|
|
138 / 7739
|
|
4
|
(HPO:0005244)
|
Gastrointestinal infarctions |
Frequent [Orphanet]
|
|
|
|
14 / 7739
|
|
5
|
(HPO:0001097)
|
Keratoconjunctivitis sicca |
Occasional [Orphanet]
|
|
|
|
25 / 7739
|
|
6
|
(HPO:0005059)
|
Arthralgia/arthritis |
Frequent [Orphanet]
|
|
|
|
141 / 7739
|
|
7
|
(HPO:0100769)
|
Synovitis |
Frequent [Orphanet]
|
|
|
|
86 / 7739
|
|
8
|
(HPO:0002239)
|
Gastrointestinal hemorrhage |
Occasional [Orphanet]
|
|
|
|
97 / 7739
|
|
9
|
(HPO:0001399)
|
Hepatic failure |
Frequent [Orphanet]
|
|
|
|
80 / 7739
|
|
10
|
(HPO:0000093)
|
Proteinuria |
Frequent [Orphanet]
|
|
|
|
169 / 7739
|
|
11
|
(HPO:0001396)
|
Cholestasis |
Frequent [Orphanet]
|
|
|
|
136 / 7739
|
|
12
|
(HPO:0002027)
|
Abdominal pain |
Frequent [Orphanet]
|
|
|
|
184 / 7739
|
|
13
|
(HPO:0000790)
|
Hematuria |
Frequent [Orphanet]
|
|
|
|
106 / 7739
|
|
14
|
(HPO:0012089)
|
Arteritis |
Very frequent [Orphanet]
|
|
|
|
40 / 7739
|
|
15
|
(HPO:0001063)
|
Acrocyanosis |
Very frequent [Orphanet]
|
|
|
|
56 / 7739
|
|
16
|
(HPO:0001744)
|
Splenomegaly |
Frequent [Orphanet]
|
|
|
|
337 / 7739
|
|
17
|
(HPO:0002240)
|
Hepatomegaly |
Frequent [Orphanet]
|
|
|
|
467 / 7739
|
|
18
|
(HPO:0000083)
|
Renal insufficiency |
Frequent [Orphanet]
|
|
|
|
232 / 7739
|
|
19
|
(HPO:0100758)
|
Gangrene |
Frequent [Orphanet]
|
|
|
|
25 / 7739
|
|
20
|
(HPO:0001945)
|
Fever |
Very frequent [Orphanet]
|
|
|
|
218 / 7739
|
|
21
|
(HPO:0100721)
|
Mediastinal lymphadenopathy |
Very frequent [Orphanet]
|
|
|
|
19 / 7739
|
|
22
|
(HPO:0100820)
|
Glomerulopathy |
Frequent [Orphanet]
|
|
|
|
46 / 7739
|
|
23
|
(HPO:0000822)
|
Hypertension |
|
|
|
|
224 / 7739
|
|
24
|
(HPO:0001871)
|
Abnormality of blood and blood-forming tissues |
|
|
|
|
37 / 7739
|
|
25
|
(HPO:0001933)
|
Subcutaneous hemorrhage |
Very frequent [Orphanet]
|
|
|
|
50 / 7739
|
|
26
|
(HPO:0003259)
|
Elevated serum creatinine |
|
|
|
|
31 / 7739
|
|
27
|
(HPO:0012050)
|
Anasarca |
|
|
|
|
4 / 7739
|
|
28
|
(HPO:0100778)
|
Cryoglobulinemia |
|
|
|
|
2 / 7739
|
|
29
|
(HPO:0012622)
|
Chronic kidney disease |
|
|
|
|
32 / 7739
|
|
30
|
(HPO:0001324)
|
Muscle weakness |
Very frequent [Orphanet]
|
|
|
|
859 / 7739
|
|
31
|
(HPO:0002242)
|
Abnormality of the intestine |
Occasional [Orphanet]
|
|
|
|
42 / 7739
|
|
32
|
(HPO:0000006)
|
Autosomal dominant inheritance |
|
|
|
|
2518 / 7739
|