|
1
|
(HPO:0004848)
|
Ph-positive acute lymphoblastic leukemia |
|
|
|
|
1 / 7739
|
|
2
|
(HPO:0005506)
|
Chronic myelogenous leukemia |
|
|
|
|
3 / 7739
|
|
3
|
(OMIM)
|
Low leukocyte alkaline phosphatase activity |
|
|
|
|
1 / 7739
|
|
4
|
(OMIM)
|
Presence of the Philadelphia chromosome (translocation of 9q34 and 22q11) in greater than 95% of patients |
|
|
|
|
1 / 7739
|
|
5
|
(OMIM)
|
Two alternative chimeric oncogene products called p210(BCR-ABL) and p185(BCR-ABL) |
|
|
|
|
1 / 7739
|
|
6
|
(OMIM)
|
Detection by RT-PCR, Southern blot analysis, and FISH for primary diagnosis and follow up for residual disease |
|
|
|
|
1 / 7739
|
|
7
|
(HPO:0001428)
|
Somatic mutation |
|
|
|
|
100 / 7739
|