1
|
(HPO:0006530)
|
Interstitial pulmonary disease |
Very frequent [IBIS]
|
|
24424167
|
IBIS
|
26 / 7739
|
2
|
(HPO:0002093)
|
Respiratory insufficiency |
Very frequent [IBIS]
|
|
25674228
|
IBIS
|
410 / 7739
|
3
|
(HPO:0005952)
|
Decreased pulmonary function |
Very frequent [IBIS]
|
|
24342432
|
IBIS
|
8 / 7739
|
4
|
(HPO:0011945)
|
Bronchiolitis obliterans organizing pneumonia |
Very frequent [IBIS]
|
|
24342432
|
IBIS
|
2 / 7739
|
5
|
(OMIM)
|
Reduced diffusion capacity |
Frequent [IBIS]
|
86% (n=94)
|
25674228
|
IBIS
|
8 / 7739
|
6
|
(HPO:0002206)
|
Pulmonary fibrosis |
Frequent [IBIS]
|
81% (n=26)
|
24342432
|
IBIS
|
51 / 7739
|
7
|
(HPO:0002795)
|
Functional respiratory abnormality |
Frequent [IBIS]
|
68% (n=94)
|
3965933
|
IBIS
|
13 / 7739
|
8
|
(HPO:0002097)
|
Emphysema |
Frequent [IBIS]
|
62% (n=26)
|
24342432
|
IBIS
|
40 / 7739
|
9
|
(HPO:0002094)
|
Dyspnea |
Frequent [IBIS]
|
57% (n=72)
|
23114922
|
IBIS
|
132 / 7739
|
10
|
(MedDRA:10025080)
|
Lung consolidation |
Frequent [IBIS]
|
57% (n=72)
|
23114922
|
IBIS
|
5 / 7739
|
11
|
(HPO:0012735)
|
Cough |
Frequent [IBIS]
|
53% (n=72)
|
23114922
|
IBIS
|
24 / 7739
|
12
|
(HPO:0001945)
|
Fever |
Frequent [IBIS]
|
47% (n=72)
|
23114922
|
IBIS
|
218 / 7739
|
13
|
(HPO:0002207)
|
Diffuse reticular or finely nodular infiltrations |
Frequent [IBIS]
|
42% (n=26)
|
24342432
|
IBIS
|
11 / 7739
|
14
|
(OMIM)
|
Radiograph shows ground glass appearance |
Frequent [IBIS]
|
|
15459629, 25493105
|
IBIS
|
7 / 7739
|
15
|
(HPO:0002111)
|
Restrictive deficit on pulmonary function testing |
Frequent [IBIS]
|
|
24424167
|
IBIS
|
25 / 7739
|
16
|
(HPO:0012418)
|
Hypoxemia |
Occasional [IBIS]
|
27% (n=26)
|
24342432
|
IBIS
|
18 / 7739
|
17
|
(HPO:0002202)
|
Pleural effusion |
Occasional [IBIS]
|
24% (n=72)
|
23114922
|
IBIS
|
22 / 7739
|
18
|
(MedDRA:10054949)
|
Metaplasia |
Occasional [IBIS]
|
19% (n=26)
|
24342432
|
IBIS
|
1 / 7739
|
19
|
(HPO:0002102)
|
Pleuritis |
Occasional [IBIS]
|
19% (n=26)
|
24342432
|
IBIS
|
7 / 7739
|
20
|
(HPO:0002110)
|
Bronchiectasis |
Occasional [IBIS]
|
15% (n=26)
|
24342432
|
IBIS
|
73 / 7739
|
21
|
(HPO:0002105)
|
Hemoptysis |
Occasional [IBIS]
|
15% (n=72)
|
23114922
|
IBIS
|
30 / 7739
|
22
|
(MedDRA:10025482)
|
Malaise |
Occasional [IBIS]
|
13% (n=72)
|
23114922
|
IBIS
|
4 / 7739
|
23
|
(MedDRA:10047924)
|
Wheezing |
Occasional [IBIS]
|
8% (n=72)
|
23114922
|
IBIS
|
8 / 7739
|
24
|
(HPO:0002113)
|
Pulmonary infiltrates |
|
|
25674228
|
IBIS
|
36 / 7739
|
25
|
(HPO:0011227)
|
Elevated C-reactive protein level |
|
|
25674228
|
IBIS
|
55 / 7739
|
26
|
(OMIM)
|
Cough, nonproductive |
|
|
25560867
|
IBIS
|
5 / 7739
|
27
|
(HPO:0100749)
|
Chest pain |
|
|
25560867
|
IBIS
|
92 / 7739
|
28
|
(HPO:0012415)
|
Abnormal blood gas level |
|
|
24460438
|
IBIS
|
9 / 7739
|
29
|
(HPO:0012176)
|
Abnormality of natural killer cells |
|
|
24889556
|
IBIS
|
2 / 7739
|
30
|
(MedDRA:10068496)
|
Natural killer cell count increased |
|
|
24889556
|
IBIS
|
1 / 7739
|
31
|
(OMIM)
|
Pulmonary fibrosis with fibroblast foci on histology |
|
|
23001801
|
IBIS
|
3 / 7739
|
32
|
(HPO:0003565)
|
Elevated erythrocyte sedimentation rate |
|
|
10602956
|
IBIS
|
31 / 7739
|
33
|
(HPO:0001824)
|
Weight loss |
|
|
25560867
|
IBIS
|
42 / 7739
|
34
|
(HPO:0012378)
|
Fatigue |
|
|
1623812
|
IBIS
|
50 / 7739
|
35
|
(HPO:0001974)
|
Leukocytosis |
|
|
23696931
|
IBIS
|
33 / 7739
|
36
|
(MedDRA:10062049)
|
Lymphocytic infiltration |
|
|
23696931
|
IBIS
|
9 / 7739
|
37
|
(HPO:0001667)
|
Right ventricular hypertrophy |
|
|
23696931
|
IBIS
|
23 / 7739
|
38
|
(HPO:0001648)
|
Cor pulmonale |
|
|
23696931
|
IBIS
|
16 / 7739
|
39
|
(HPO:0002109)
|
Abnormality of the bronchi |
|
|
24342432
|
IBIS
|
6 / 7739
|
40
|
(HPO:0030166)
|
Night sweats |
|
|
14533463
|
IBIS
|
3 / 7739
|
41
|
(HPO:0002789)
|
Tachypnea |
|
|
8252981
|
IBIS
|
48 / 7739
|
42
|
(HPO:0002792)
|
Reduced vital capacity |
|
|
21702658
|
IBIS
|
17 / 7739
|
43
|
(OMIM)
|
Reduced forced vital capacity |
|
|
11961300
|
IBIS
|
3 / 7739
|
44
|
(MedDRA:10016987)
|
Forced expiratory volume decreased |
|
|
11961300
|
IBIS
|
2 / 7739
|
45
|
(MedDRA:10065906)
|
Carbon monoxide diffusing capacity decreased |
|
|
8685496
|
IBIS
|
8 / 7739
|