|
1
|
(HPO:0000132)
|
Menorrhagia |
|
|
|
|
40 / 7739
|
|
2
|
(HPO:0000225)
|
Gingival bleeding |
|
|
|
|
28 / 7739
|
|
3
|
(HPO:0000421)
|
Epistaxis |
|
|
|
|
85 / 7739
|
|
4
|
(HPO:0000978)
|
Bruising susceptibility |
|
|
|
|
123 / 7739
|
|
5
|
(HPO:0002239)
|
Gastrointestinal hemorrhage |
|
|
|
|
97 / 7739
|
|
6
|
(HPO:0003010)
|
Prolonged bleeding time |
|
|
|
|
88 / 7739
|
|
7
|
(HPO:0003645)
|
Prolonged partial thromboplastin time |
|
|
|
|
20 / 7739
|
|
8
|
(HPO:0005261)
|
Joint hemorrhage |
|
|
|
|
17 / 7739
|
|
9
|
(HPO:0008151)
|
Prolonged prothrombin time |
|
|
|
|
13 / 7739
|
|
10
|
(HPO:0012201)
|
Reduced prothrombin activity |
|
|
|
|
4 / 7739
|
|
11
|
(MedDRA:10018852)
|
Haematoma |
|
|
|
|
6 / 7739
|
|
12
|
(OMIM)
|
Umbilical cord hemorrhage |
|
|
|
|
1 / 7739
|
|
13
|
(OMIM)
|
Intracranial bleeding |
|
|
|
|
4 / 7739
|
|
14
|
(OMIM)
|
Bleeding tendency due to defect in prothrombin and inability to form fibrin clot |
|
|
|
|
1 / 7739
|
|
15
|
(OMIM)
|
Decreased F2 antigen levels (in some patients) |
|
|
|
|
1 / 7739
|
|
16
|
(OMIM)
|
Decreased F2 activity |
|
|
|
|
1 / 7739
|
|
17
|
(HPO:0000007)
|
Autosomal recessive inheritance |
|
|
|
|
2538 / 7739
|
|
18
|
(HPO:0003577)
|
Congenital onset |
|
|
|
|
133 / 7739
|
|
19
|
(HPO:0003828)
|
Variable expressivity |
|
|
|
|
130 / 7739
|