1
|
(HPO:0000710)
|
Hyperorality |
|
|
|
|
6 / 7739
|
2
|
(HPO:0000713)
|
Agitation |
|
|
|
|
18 / 7739
|
3
|
(HPO:0000734)
|
Disinhibition |
|
|
|
|
13 / 7739
|
4
|
(HPO:0000738)
|
Hallucinations |
|
|
|
|
60 / 7739
|
5
|
(HPO:0000741)
|
Apathy |
|
|
|
|
42 / 7739
|
6
|
(HPO:0000751)
|
Personality changes |
|
|
|
|
33 / 7739
|
7
|
(HPO:0001300)
|
Parkinsonism |
|
|
|
|
75 / 7739
|
8
|
(HPO:0002120)
|
Cerebral cortical atrophy |
|
|
|
|
187 / 7739
|
9
|
(HPO:0002145)
|
Frontotemporal dementia |
|
|
|
|
14 / 7739
|
10
|
(HPO:0002171)
|
Gliosis |
|
|
|
|
48 / 7739
|
11
|
(HPO:0002186)
|
Apraxia |
|
|
|
|
22 / 7739
|
12
|
(HPO:0002300)
|
Mutism |
|
|
|
|
28 / 7739
|
13
|
(HPO:0002354)
|
Memory impairment |
|
|
|
|
63 / 7739
|
14
|
(HPO:0002357)
|
Dysphasia |
|
|
|
|
33 / 7739
|
15
|
(HPO:0002381)
|
Aphasia |
|
|
|
|
27 / 7739
|
16
|
(HPO:0002529)
|
Neuronal loss in central nervous system |
|
|
|
|
37 / 7739
|
17
|
(HPO:0002591)
|
Polyphagia |
|
|
|
|
25 / 7739
|
18
|
(HPO:0006956)
|
Dilation of lateral ventricles |
|
|
|
|
13 / 7739
|
19
|
(HPO:0007064)
|
Progressive language deterioration |
|
|
|
|
3 / 7739
|
20
|
(HPO:0008762)
|
Repetitive compulsive behavior |
|
|
|
|
1 / 7739
|
21
|
(OMIM)
|
Cognitive impairment, gradual onset |
|
|
|
|
1 / 7739
|
22
|
(OMIM)
|
Speech hesitancy |
|
|
|
|
1 / 7739
|
23
|
(MedDRA:10034703)
|
Perseveration |
|
|
|
|
3 / 7739
|
24
|
(OMIM)
|
Reading comprehension deficits |
|
|
|
|
1 / 7739
|
25
|
(OMIM)
|
Nonfluent aphasia |
|
|
|
|
1 / 7739
|
26
|
(OMIM)
|
Motor neuron disease |
|
|
|
|
2 / 7739
|
27
|
(OMIM)
|
Cerebral cortical atrophy, especially frontal lobes |
|
|
|
|
1 / 7739
|
28
|
(OMIM)
|
Ubiquitin-positive cytoplasmic and intranuclear neuronal inclusions |
|
|
|
|
1 / 7739
|
29
|
(OMIM)
|
Amyloid plaques may be present |
|
|
|
|
1 / 7739
|
30
|
(OMIM)
|
Neurofibrillary tangles may be present |
|
|
|
|
2 / 7739
|
31
|
(OMIM)
|
No Pick bodies or Lewy bodies |
|
|
|
|
1 / 7739
|
32
|
(OMIM)
|
No tau pathology |
|
|
|
|
1 / 7739
|
33
|
(OMIM)
|
Cortical and brainstem neuronal loss |
|
|
|
|
1 / 7739
|
34
|
(OMIM)
|
Astrocytic gliosis |
|
|
|
|
1 / 7739
|
35
|
(OMIM)
|
Nonspecific spongiform degeneration |
|
|
|
|
1 / 7739
|
36
|
(OMIM)
|
Microvacuolation |
|
|
|
|
1 / 7739
|
37
|
(MedDRA:10066364)
|
Hypersexuality |
|
|
|
|
1 / 7739
|
38
|
(HPO:0000719)
|
Inappropriate behavior |
|
|
|
|
5 / 7739
|
39
|
(HPO:0000711)
|
Restlessness |
|
|
|
|
18 / 7739
|
40
|
(HPO:0000006)
|
Autosomal dominant inheritance |
|
|
|
|
2518 / 7739
|
41
|
(HPO:0030214)
|
Hypersexuality |
|
|
|
|
2 / 7739
|
42
|
(HPO:0030223)
|
Perseveration |
|
|
|
|
5 / 7739
|