|
1
|
(HPO:0000132)
|
Menorrhagia |
|
|
|
|
40 / 7739
|
|
2
|
(HPO:0000421)
|
Epistaxis |
|
|
|
|
85 / 7739
|
|
3
|
(HPO:0000471)
|
Gastrointestinal angiodysplasia |
|
|
|
|
3 / 7739
|
|
4
|
(HPO:0000978)
|
Bruising susceptibility |
|
|
|
|
123 / 7739
|
|
5
|
(HPO:0001634)
|
Mitral valve prolapse |
|
|
|
|
69 / 7739
|
|
6
|
(HPO:0001650)
|
Aortic valve stenosis |
|
|
|
|
49 / 7739
|
|
7
|
(HPO:0002239)
|
Gastrointestinal hemorrhage |
|
|
|
|
97 / 7739
|
|
8
|
(HPO:0003010)
|
Prolonged bleeding time |
|
|
|
|
88 / 7739
|
|
9
|
(HPO:0003125)
|
Reduced factor VIII activity |
|
|
|
|
13 / 7739
|
|
10
|
(HPO:0003540)
|
Impaired platelet aggregation |
|
|
|
|
17 / 7739
|
|
11
|
(HPO:0005261)
|
Joint hemorrhage |
|
|
|
|
17 / 7739
|
|
12
|
(HPO:0005542)
|
Prolonged whole-blood clotting time |
|
|
|
|
5 / 7739
|
|
13
|
(OMIM)
|
Prolonged bleeding time due to quantitative decrease of VWF protein |
|
|
|
|
1 / 7739
|
|
14
|
(OMIM)
|
Defect in platelet aggregation |
|
|
|
|
6 / 7739
|
|
15
|
(OMIM)
|
Mucocutaneous bleeding |
|
|
|
|
7 / 7739
|
|
16
|
(OMIM)
|
Decreased levels of plasma VWF antigen |
|
|
|
|
1 / 7739
|
|
17
|
(OMIM)
|
Decreased levels of plasma factor VIII |
|
|
|
|
1 / 7739
|
|
18
|
(HPO:0000006)
|
Autosomal dominant inheritance |
|
|
|
|
2518 / 7739
|
|
19
|
(HPO:0003829)
|
Incomplete penetrance |
|
|
|
|
85 / 7739
|