|
1
|
(HPO:0007404)
|
Nonepidermolytic palmoplantar keratoderma |
|
|
|
|
1 / 7739
|
|
2
|
(OMIM)
|
Smooth, waxy, thick skin over palms and soles, desquamating in large flakes |
|
|
|
|
1 / 7739
|
|
3
|
(OMIM)
|
Well-defined erythematous border |
|
|
|
|
1 / 7739
|
|
4
|
(OMIM)
|
Deep fissures of skin creases |
|
|
|
|
1 / 7739
|
|
5
|
(OMIM)
|
Skin over joint surfaces of hands and feet is thick, red, and edematous |
|
|
|
|
1 / 7739
|
|
6
|
(OMIM)
|
Hyperkeratosis of skin at nipples and umbilicus |
|
|
|
|
1 / 7739
|
|
7
|
(OMIM)
|
Hyperkeratosis of stratum corneum |
|
|
|
|
3 / 7739
|
|
8
|
(OMIM)
|
No cytolysis |
|
|
|
|
1 / 7739
|
|
9
|
(OMIM)
|
No abnormal keratohyalin granules |
|
|
|
|
1 / 7739
|
|
10
|
(OMIM)
|
No aggregated tonofilaments |
|
|
|
|
2 / 7739
|
|
11
|
(OMIM)
|
No large keratohyalin granules |
|
|
|
|
2 / 7739
|
|
12
|
(HPO:0000006)
|
Autosomal dominant inheritance |
|
|
|
|
2518 / 7739
|