|
1
|
(HPO:0001288)
|
Gait disturbance |
|
|
|
|
318 / 7739
|
|
2
|
(HPO:0001300)
|
Parkinsonism |
|
|
|
|
75 / 7739
|
|
3
|
(HPO:0001332)
|
Dystonia |
|
|
|
|
197 / 7739
|
|
4
|
(HPO:0001337)
|
Tremor |
|
|
|
|
200 / 7739
|
|
5
|
(HPO:0001347)
|
Hyperreflexia |
|
|
|
|
363 / 7739
|
|
6
|
(HPO:0002063)
|
Rigidity |
|
|
|
|
92 / 7739
|
|
7
|
(HPO:0002067)
|
Bradykinesia |
|
|
|
|
62 / 7739
|
|
8
|
(HPO:0002172)
|
Postural instability |
|
|
|
|
22 / 7739
|
|
9
|
(HPO:0011960)
|
Substantia nigra gliosis |
|
|
|
|
4 / 7739
|
|
10
|
(OMIM)
|
Parkinsonism, early-onset |
|
|
|
|
1 / 7739
|
|
11
|
(OMIM)
|
Hyperreflexia may occur |
|
|
|
|
1 / 7739
|
|
12
|
(OMIM)
|
Diurnal fluctuations of symptoms (in a subset of patients) |
|
|
|
|
1 / 7739
|
|
13
|
(HPO:0000726)
|
Dementia |
|
|
|
|
131 / 7739
|
|
14
|
(OMIM)
|
Neuronal loss and gliosis in the substantia nigra pars compacta |
|
|
|
|
2 / 7739
|
|
15
|
(OMIM)
|
Neuronal loss in the locus ceruleus |
|
|
|
|
1 / 7739
|
|
16
|
(OMIM)
|
No Lewy bodies |
|
|
|
|
2 / 7739
|
|
17
|
(HPO:0000007)
|
Autosomal recessive inheritance |
|
|
|
|
2538 / 7739
|
|
18
|
(HPO:0003581)
|
Adult onset |
|
|
|
|
117 / 7739
|