CURVED NAIL OF FOURTH TOE

General Information (adopted from Orphanet):

Synonyms, Signs: CLAW-LIKE FINGERS AND TOES
Number of Symptoms 13
OrphanetNr:
OMIM Id: 219070
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal recessive inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0009882) Short distal phalanx of finger 125 / 7739
2
(HPO:0008393) Congenital curved nail of fourth toe 1 / 7739
3
(HPO:0001812) Hyperconvex fingernails 3 / 7739
4
(OMIM) Short terminal phalanges 5 / 7739
5
(OMIM) Tubular nails, fifth fingers 1 / 7739
6
(OMIM) Blunt, Y-shaped bony projection of distal phalanges 1 / 7739
7
(OMIM) Short, spear-shaped terminal phalanges 1 / 7739
8
(HPO:0000007) Autosomal recessive inheritance 2538 / 7739
9
(OMIM) No crescent-shaped cap of terminal phalanges 1 / 7739
10
(OMIM) Congenital curved nail, fourth toe 1 / 7739
11
(OMIM) Claw-like fourth toes 1 / 7739
12
(OMIM) Tubular nails, fifth toes 1 / 7739
13
(OMIM) Claw-like fourth and fifth fingers 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Clinical Description OMIM Iwasawa et al. (1991) described a congenital curved nail of the fourth toe in 5 children, 3 of whom were sibs. No definitely identical condition was found in the literature.

Egawa (1977) described a 22-year-old woman ...