Baughman (1971) described a seemingly distinct 'new' syndrome characterized by curly hair and hypoplastic nails with congenital ankyloblepharon (fusion of eyelids).
Toriello (1994) suggested that the disorder reported by Ohishi et al. (1991) as a possibly ... Baughman (1971) described a seemingly distinct 'new' syndrome characterized by curly hair and hypoplastic nails with congenital ankyloblepharon (fusion of eyelids). Toriello (1994) suggested that the disorder reported by Ohishi et al. (1991) as a possibly new autosomal recessive ectodermal dysplasia was an example of CHANDS. Ohishi et al. (1991) reported a patient with alveolar synechia, ankyloblepharon, bilateral commissural lip pits, and inferiorly attached frenulum, hypoplastic nails, and woolly scalp hair. The parents were consanguineous, and the mother had congenital absence of the right upper second incisor and the left upper canine. The proband's older sister also had a congenital defect of the left upper deciduous canine, as well as a right inguinal hernia.