LUNG CANCERALVEOLAR CELL CARCINOMA, INCLUDED

General Information (adopted from Orphanet):

Synonyms, Signs: LUNG CANCER, PROTECTION AGAINST, INCLUDED
NONSMALL CELL LUNG CANCER, INCLUDED
ADENOCARCINOMA OF LUNG, INCLUDED
Number of Symptoms 3
OrphanetNr:
OMIM Id: 211980
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal recessive inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0006519) Alveolar cell carcinoma 3 / 7739
2
(OMIM) Non-small-cell cancer 1 / 7739
3
(HPO:0000007) Autosomal recessive inheritance 2538 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Lung cancer is the leading cause of cancer deaths in the U.S. and worldwide. The 2 major forms of lung cancer are nonsmall cell lung cancer and small cell lung cancer (see 182280), which account for 85% and ...
Clinical Description OMIM Joishy et al. (1977) described identical twins who developed symptoms of alveolar cell carcinoma almost simultaneously.

Ahrendt et al. (2001) noted that incidence rates for squamous cell and small cell lung carcinoma began falling among males ...

Molecular genetics OMIM Ding et al. (2008) sequenced 623 genes with known or potential relationship to cancer in 188 human lung adenocarcinomas. Their analysis identified 26 genes that are mutated at significantly high frequencies and are probably involved in carcinogenesis. The ...
Population genetics OMIM Haiman et al. (2006) investigated differences in the risk of lung cancer associated with cigarette smoking in 183,813 African American, Japanese American, Latino, Native Hawaiian, and white men and women. Their analysis included 1,979 cases of incident lung ...