TUNE DEAFNESS

General Information (adopted from Orphanet):

Synonyms, Signs: TONE DEAFNESS
AMUSIA, CONGENITAL
DYSMELODIA
Number of Symptoms 3
OrphanetNr:
OMIM Id: 191200
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0000365) Hearing impairment 539 / 7739
2
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739
3
(OMIM) Tune deafness 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Tune deafness, or congenital amusia, is a lifelong deficient in music perception that cannot be explained by hearing loss, brain damage, intellectual deficiencies, or lack of exposure. The disorder affects predominantly the melodic pitch dimension (summary by Peretz ...
Clinical Description OMIM Peretz et al. (2002) reported a middle-aged woman with congenital amusia, an impairment of the ability to discriminate, recognize, and appreciate melody since birth. She had no cognitive deficits, brain lesions, hearing loss, or socioaffective disturbances, and was ...
Population genetics OMIM Kalmus and Fry (1980) estimated that the frequency of tune deafness in the British population is 4.2%.