TEETH, ODD SHAPES OFLOBODONTIA, INCLUDED

General Information (adopted from Orphanet):

Synonyms, Signs: CONICAL TEETH, MULTIPLE, INCLUDED
Number of Symptoms 8
OrphanetNr:
OMIM Id: 187000
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0000164) Abnormality of the teeth 291 / 7739
2
(OMIM) Exaggerated middle labial lobes of canines 1 / 7739
3
(OMIM) Large number of molar cusps 1 / 7739
4
(OMIM) Partial tooth pegging 1 / 7739
5
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739
6
(OMIM) Reduced premolar size 1 / 7739
7
(OMIM) Deep lingual tooth pits 1 / 7739
8
(OMIM) Odd shaped teeth 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Clinical Description OMIM Robbins and Keene (1964) reported a 19-year-old boy whose teeth showed partial pegging, deep lingual pits, exaggeration of middle labial lobes of the canines, and reduced premolar size. One sib was normal. In 5 generations, 10 persons showed ...