T-CELL LEUKEMIA/LYMPHOMA 1A
General Information (adopted from Orphanet):
| Synonyms, Signs: |
LYMPHOMA/LEUKEMIA, T-CELL TCL1A TCL1 |
| Number of Symptoms | 2 |
| OrphanetNr: | |
| OMIM Id: |
186960
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| ICD-10: |
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| UMLs: |
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| MeSH: |
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| MedDRA: |
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| Snomed: |
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Prevalence, inheritance and age of onset:
| Prevalence: | No data available. |
| Inheritance: |
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| Age of onset: |
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Disease classification (adopted from Orphanet):
| Parent Diseases: | No data available. |
Symptom Information:
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(HPO:0001909) | Leukemia | 46 / 7739 | ||||
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(HPO:0005517) | T-cell lymphoma/leukemia | 3 / 7739 |
Associated genes:
ClinVar (via SNiPA)
| Gene symbol | Variation | Clinical significance | Reference |
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Additional Information:
| Description: (OMIM) |
Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (see 186880) or ... |