Hyperplastic polyposis syndrome
General Information (adopted from Orphanet):
| Synonyms, Signs: |
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| Number of Symptoms | 2 |
| OrphanetNr: | 157798 |
| OMIM Id: |
175020
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| ICD-10: |
D12.6 |
| UMLs: |
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| MeSH: |
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| MedDRA: |
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| Snomed: |
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Prevalence, inheritance and age of onset:
| Prevalence: | 50 of 100 000 [Orphanet] |
| Inheritance: |
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| Age of onset: |
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Disease classification (adopted from Orphanet):
| Parent Diseases: |
Genetic intestinal polyposis
-Rare genetic disease Inherited cancer-predisposing syndrome -Rare genetic disease -Rare oncologic disease Intestinal polyposis syndrome -Rare gastroenterologic disease -Rare oncologic disease |
Symptom Information:
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(HPO:0004394) | Multiple gastric polyps | 9 / 7739 | ||||
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(OMIM) | Stomach adenocarcinoma propensity | 1 / 7739 |
Associated genes:
ClinVar (via SNiPA)
| Gene symbol | Variation | Clinical significance | Reference |
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Additional Information:
| Clinical Description OMIM |
Dos Santos and de Magalhaes (1980) described a family in which 10 members of 3 generations had multiple polyposis, with adenocarcinomatous propensities, limited to the stomach. No male-to-male transmission was observed. Seruca et al. (1991) restudied the family ... |