OSTEOPOROSIS

General Information (adopted from Orphanet):

Synonyms, Signs: OSTEOPOROSIS, INVOLUTIONAL FRACTURE, HIP, SUSCEPTIBILITY TO, INCLUDED
OSTEOPOROSIS, POSTMENOPAUSAL
BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS
BMND
Number of Symptoms 3
OrphanetNr:
OMIM Id: 166710
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0000939) Osteoporosis 129 / 7739
2
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739
3
(MedDRA:10031285) Osteoporosis postmenopausal 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Clinical Description OMIM Using dual-photon absorptiometry, Seeman et al. (1989) demonstrated reduced bone mass in the lumbar spine and perhaps in the femoral neck of premenopausal daughters of postmenopausal women with osteoporotic compression fractures. The findings suggested that genetic factors, expressed ...
Molecular genetics OMIM Prockop (1998) reviewed the search for the genetic basis of osteoporosis. In a review of the genetics of osteoporosis, Giguere and Rousseau (2000) stated that twin studies had shown that genetic factors account for up to 80% of ...