PERMANENT MOLARS, SECONDARY RETENTION OF

General Information (adopted from Orphanet):

Synonyms, Signs: ANKYLOSIS OF TEETH
DENTAL ANKYLOSIS
MOLAR I REINCLUSION
Number of Symptoms 7
OrphanetNr:
OMIM Id: 157950
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0000303) Mandibular prognathia 179 / 7739
2
(HPO:0000164) Abnormality of the teeth 291 / 7739
3
(HPO:0004209) Clinodactyly of the 5th finger 288 / 7739
4
(OMIM) Failure of premolars and molars to meet at occlusal plane 1 / 7739
5
(OMIM) Reduced lower facial height 1 / 7739
6
(OMIM) Ankylosed teeth 1 / 7739
7
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Secondary retention is the cessation of eruption of a tooth after emergence that does not result from a physical barrier in the path of eruption or an abnormal position of the tooth. Permanent molars are less frequently affected ...
Clinical Description OMIM Via (1964) suggested autosomal dominant inheritance for submerged deciduous molars. Bosker and Nijenhuis (1975) performed linkage studies using blood and serum groups in 5 pedigrees segregating autosomal dominant reinclusion of the first molar and found suggestive linkage to ...