MIGRAINE WITH OR WITHOUT AURA, SUSCEPTIBILITY TO, 1

General Information (adopted from Orphanet):

Synonyms, Signs: MIGRAINE
MGR1
MA
MGAU
Number of Symptoms 9
OrphanetNr:
OMIM Id: 157300
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0000613) Photophobia 158 / 7739
2
(HPO:0002077) Migraine with aura 14 / 7739
3
(HPO:0002183) Phonophobia 10 / 7739
4
(HPO:0002083) Migraine without aura 8 / 7739
5
(HPO:0002018) Nausea 44 / 7739
6
(HPO:0002013) Vomiting 191 / 7739
7
(OMIM) Pulsating quality 3 / 7739
8
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739
9
(OMIM) Headache is unilateral 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Migraine is the most common type of chronic, episodic headache, as summarized by Featherstone (1985).

One locus for migraine with or without aura (MGR1) has been identified on chromosome 4q24. Other loci for migraine have been ...

Clinical Description OMIM Most cases of migraine are of the mild rather than the classic type, which has prodromal neurologic deficit and severe, focal head pain. Since no biochemical marker for migraine has been found, migraine and its variants remain a ...
Molecular genetics OMIM In different populations, Kowa et al. (2000), Oterino et al. (2004), and Scher et al. (2006) found associations between migraine with aura and a 677CT polymorphism in the MTHFR gene (607093.0003).
Population genetics OMIM This very frequent and sometimes incapacitating condition affects about 4% of children, 6% of men, and 18% of women (Stewart et al., 1992). In a random-digit dialing prevalence study of migraine as diagnosed by the International Headache Society ...