NAIL DISORDER, NONSYNDROMIC CONGENITAL, 2

General Information (adopted from Orphanet):

Synonyms, Signs: KOILONYCHIA, HEREDITARY
SPOON NAILS KOILONYCHIA WITH LEUKONYCHIA, INCLUDED
NDNC2
Number of Symptoms 4
OrphanetNr:
OMIM Id: 149300
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0001598) Concave nail 14 / 7739
2
(OMIM) Spoon-shaped fingernails (koilonychia), thumb, index, and middle fingers most severely affected 1 / 7739
3
(OMIM) Spoon-shaped toenails 1 / 7739
4
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Koilonychia, or 'spoon nails,' is a relatively uncommon disorder in which the nails are abnormally thin and concave from side to side, with the edges turned up. Single or multiple fingers and/or toes may be involved (summary by ...
Clinical Description OMIM Hellier (1950) reported a family in which 14 individuals over 4 generations had koilonychia. The proband was a 73-year-old man who did not complain of his nails but was observed to have marked koilonychia of all the nails ...