HYPERTENSION, ESSENTIAL

General Information (adopted from Orphanet):

Synonyms, Signs: EHT
Number of Symptoms 4
OrphanetNr:
OMIM Id: 145500
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Multifactorial
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0004972) Elevated mean arterial pressure 1 / 7739
2
(HPO:0004421) Elevated systolic blood pressure 2 / 7739
3
(HPO:0005117) Elevated diastolic blood pressure 2 / 7739
4
(HPO:0001426) Multifactorial inheritance 37 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) The Pickering school held that blood pressure has a continuous distribution, that multiple genes and multiple environmental factors determine the level of one's blood pressure just as the determination of stature and intelligence is multifactorial, and that 'essential ...
Clinical Description OMIM Ravogli et al. (1990) measured blood pressure in 15 normotensive subjects whose parents were both hypertensive (FH+/+), 15 normotensive subjects with 1 hypertensive parent (FH +/-), and 15 normotensive subjects whose parents were not hypertensive (FH -/-); among ...
Molecular genetics OMIM In a review, Garbers and Dubois (1999) identified a number of important blood pressure regulatory genes, including their loci in the human, mouse, and rat genomes. Phenotypes of gene deletions and overexpression in mice were summarized, and a ...