DEVELOPMENTAL DYSPLASIA OF THE HIP 1

General Information (adopted from Orphanet):

Synonyms, Signs: CDH, INCLUDED
HIP DYSPLASIA, CONGENITAL, NONSYNDROMIC, INCLUDED
CONGENITAL DYSPLASIA OF THE HIP, INCLUDED
DEVELOPMENTAL DYSPLASIA OF HIP, INCLUDED
DISLOCATION OF HIP, CONGENITAL, INCLUDED
Number of Symptoms 4
OrphanetNr:
OMIM Id: 142700
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Multifactorial
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0001374) Congenital hip dislocation 51 / 7739
2
(HPO:0008807) Acetabular dysplasia 6 / 7739
3
(HPO:0001426) Multifactorial inheritance 37 / 7739
4
(OMIM) Positive Ortolani sign 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Acetabular dysplasia is an idiopathic, localized developmental dysplasia of the hip that is characterized by a shallow hip socket and decreased coverage of the femoral head (Mabuchi et al., 2006). Its radiologic criteria include the center-edge angle of ...
Clinical Description OMIM Mabuchi et al. (2006) described a large Japanese family in which acetabular dysplasia inherited as an autosomal dominant was the basis of osteoarthritis of the hip joint. Eight individuals in 4 generations had acetabular dysplasia manifested as pain ...
Population genetics OMIM There is a great discrepancy in the frequency of CDH according to geographic and ethnic differences. In general, CDH is more frequent in whites than in blacks and Chinese (Weinstein, 1987; Wilkinson, 1992). For Caucasian populations, an incidence ...