HEPATITIS B VACCINE, RESPONSE TO

General Information (adopted from Orphanet):

Synonyms, Signs: HBV VACCINE, RESPONSE TO
Number of Symptoms 4
OrphanetNr:
OMIM Id: 142395
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0012115) Hepatitis 24 / 7739
2
(OMIM) Bimodal antibody response to hepatitis B vaccine 1 / 7739
3
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739
4
(OMIM) Low response associated with MHC haplotype HLA-B8,SC01,DR3 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) More than 2 billion people have been infected with the hepatitis B virus (HBV; see 610424), and more than 350 million of these people are chronic carriers. Each year more than half a million die as a result ...
Molecular genetics OMIM Alper et al. (1989) followed up on a previous observation of a bimodal antibody response to hepatitis B vaccine, with about 14% of individuals being low responders. It had been found that the low responders included a greater-than-expected ...