GLAUCOMA 1, OPEN ANGLE, A

General Information (adopted from Orphanet):

Synonyms, Signs: GLAUCOMA, PRIMARY OPEN ANGLE, JUVENILE-ONSET, 1
GLC1L, INCLUDED
JOAG1 GLAUCOMA 1, OPEN ANGLE, L, INCLUDED
GLC1A
Number of Symptoms 2
OrphanetNr:
OMIM Id: 137750
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0000545) Myopia 286 / 7739
2
(MedDRA:10030348) Open angle glaucoma 3 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Clinical Description OMIM Impressive 'dominant' pedigrees of juvenile glaucoma were reported by Stokes (1940), Allen and Ackerman (1942), and others. In a Scottish family that settled in Virginia, Courtney and Hill (1931) described 18 cases (10 males, 8 females) in 5 ...
Molecular genetics OMIM Stone et al. (1997) used analyses of sequence tagged site (STS) content and haplotype sharing between families affected with the 1q-linked form of glaucoma to prioritize candidate genes for mutation screening. A gene encoding the trabecular meshwork protein ...