DIABETES MELLITUS, NONINSULIN-DEPENDENT

General Information (adopted from Orphanet):

Synonyms, Signs: DIABETES MELLITUS, TYPE II
MATURITY-ONSET DIABETES INSULIN RESISTANCE, SUSCEPTIBILITY TO, INCLUDED
NONINSULIN-DEPENDENT DIABETES MELLITUS
NIDDM
T2D
Number of Symptoms 5
OrphanetNr:
OMIM Id: 125853
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0005978) Type II diabetes mellitus 68 / 7739
2
(HPO:0000855) Insulin resistance 32 / 7739
3
(HPO:0003584) Late onset 10 / 7739
4
(OMIM) Decreased glucose disposal 1 / 7739
5
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Genotype-Phenotype Correlations OMIM Li et al. (2001) assessed the prevalence of families with both type I and type II diabetes in Finland and studied, in patients with type II diabetes, the association between a family history of type 1 diabetes, GAD ...
Molecular genetics OMIM - Mutation in PPAR-Gamma

Altshuler et al. (2000) confirmed an association of the common pro12-to-ala polymorphism in PPAR-gamma (601487.0002) with type II diabetes. They found a modest but significant increase in diabetes risk associated with the ...