The cardinal characteristic of this trait is that the fingertip ridges, instead of running transversely, are vertical and run off the end of the fingertips. Bilateral radial loops on the ring and little fingers (exceedingly rare in persons ... The cardinal characteristic of this trait is that the fingertip ridges, instead of running transversely, are vertical and run off the end of the fingertips. Bilateral radial loops on the ring and little fingers (exceedingly rare in persons without this syndrome) are usual. Palmar features include a tendency for interdigital patterns on the palm to be in the IVth space and to extend more proximally than normal, and the presence of a peculiar crack in the ridges of the hypothenar eminence, extending from the hypothenar pattern to the ulnar border of the palm (David et al., 1973). In the first family reported by David (1971) several other dominant traits were segregating independently. David (1973) described 2 other families with this trait as well as a third family with a similar trait (see 125530).