DERMAL RIDGES-OFF-THE-END

General Information (adopted from Orphanet):

Synonyms, Signs: RIDGES-OFF-THE-END SYNDROME
ROES
Number of Symptoms 9
OrphanetNr:
OMIM Id: 125550
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0007608) Abnormal palmar dermal ridges 3 / 7739
2
(HPO:0001211) Abnormality of the fingertips 1 / 7739
3
(OMIM) Vertical crack in ridges of hypothenar eminence 2 / 7739
4
(OMIM) Finger patterns partly cross distal interphalangeal crease 1 / 7739
5
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739
6
(OMIM) Bilateral radial loops on ring and little fingers 1 / 7739
7
(OMIM) Vertical fingertip ridges extending off the fingertips 1 / 7739
8
(OMIM) Abnormal proximal palmar region pattern 1 / 7739
9
(OMIM) Distal t triradius displacement 2 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Clinical Description OMIM The cardinal characteristic of this trait is that the fingertip ridges, instead of running transversely, are vertical and run off the end of the fingertips. Bilateral radial loops on the ring and little fingers (exceedingly rare in persons ...