DEMENTIA/PARKINSONISM WITH NON-ALZHEIMER AMYLOID PLAQUES

General Information (adopted from Orphanet):

Synonyms, Signs:
Number of Symptoms 7
OrphanetNr:
OMIM Id: 125320
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0000726) Dementia 131 / 7739
2
(HPO:0001300) Parkinsonism 75 / 7739
3
(OMIM) Extracellular hyaline eosinophilic, congophilic amyloid plaques in the cerebral cortex, basal ganglia, thalamus, and substantia nigra 1 / 7739
4
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739
5
(OMIM) atrophy and gliosis of the basal ganglia and substantia nigra 1 / 7739
6
(OMIM) Severe dementia 1 / 7739
7
(HPO:0011960) Substantia nigra gliosis 4 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: