Helweg-Larsen and Ludvigsen (1946) reported a kindred of 14 in 5 generations with anhidrosis, 5 of whom had defective hearing with onset between 35 and 45 years of age. There were no dental or hair anomalies.
... Helweg-Larsen and Ludvigsen (1946) reported a kindred of 14 in 5 generations with anhidrosis, 5 of whom had defective hearing with onset between 35 and 45 years of age. There were no dental or hair anomalies. Ellington (1951) reported 2 brothers with anhidrosis, dry skin, dental anomalies, thin hair, and sparse eyebrows. Both had hearing loss, severe in one and slight in the other, and both suffered from chronic otitis media. See also autosomal dominant deafness and onychodystrophy (124480).