Histopathology shows bone formation with trabeculae, blood-filled cavernous spaces, and cells typical of bone formation (osteoblasts, osteocytes, and osteoclasts)
Choroidal osteoma is a benign tumor found in the peripapillary region, most characteristically in one eye of otherwise healthy, young females. Histopathologic changes include bone formation with trabeculae, blood-filled cavernous spaces, and cells typical of bone formation, i.e., ... Choroidal osteoma is a benign tumor found in the peripapillary region, most characteristically in one eye of otherwise healthy, young females. Histopathologic changes include bone formation with trabeculae, blood-filled cavernous spaces, and cells typical of bone formation, i.e., osteoblasts, osteocytes, and osteoclasts. CLINICAL DESCRIPTION {2:Noble (1990)} described a family in which a girl and her monozygotic twin brothers had bilateral choroidal osteomas. The tumors showed growth between ages 11 and 13 years in the sister. The twin brothers' tumors remained stable between 9 and 11 years except for a new, isolated lesion in one eye of one of them. Their mother had a yellow mottling situated nasal to the disc in each eye resembling in appearance that in one eye in one of the twins. She showed no calcium on ultrasonography. Cuhna (1984) observed an affected mother and daughter: the 33-year-old mother had visual acuity reduced to the finger counting range in each eye since age 11 years and had bilateral peripapillary atrophic chorioretinal lesions. Her 5-year-old daughter had bilateral yellow-white lesions associated with bilateral macular hemorrhages. The familial occurrence as well as the bilaterality is consistent with the origin of the osteomas in a choristoma. A choristoma is a benign tumefaction of a chorista, which is an embryonic tissue rest composed of cellular and tissue elements not normally present at the affected site.