CENTRALOPATHIC EPILEPSY

General Information (adopted from Orphanet):

Synonyms, Signs: TEMPORAL-CENTRAL FOCAL EPILEPSY
BENIGN EPILEPSY OF CHILDHOOD WITH CENTROTEMPORAL SPIKES
CENTROTEMPORAL EPILEPSY
BENIGN ROLANDIC EPILEPSY
BECTS
ECT
Number of Symptoms 7
OrphanetNr:
OMIM Id: 117100
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Sporadic
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
 (HPO:0007334) Bilateral convulsive seizures 6 / 7739
2
 (OMIM) EEG shows unilateral centrotemporal spikes 1 / 7739
3
 (OMIM) Seizures, partial, unilateral 1 / 7739
4
 (OMIM) Seizures affect the vocal cords, lips, mouth, and face 1 / 7739
5
 (OMIM) Difficulty speaking during seizures 1 / 7739
6
 (OMIM) Gurgling or drooling during seizures 1 / 7739
7
 (OMIM) Nocturnal seizures 3 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Benign epilepsy of childhood with centrotemporal spikes (BECTS) or sharp waves, also known as rolandic epilepsy, is the most common idiopathic childhood epilepsy syndrome (Neubauer et al., 1998). It is termed 'rolandic' epilepsy because of the characteristic features ...
Clinical Description OMIM Benign centrotemporal epilepsy has a mean age of onset of 10 years and includes brief, hemifacial partial seizures that tend to become generalized, often at night. The EEG findings include slow, diphasic, high voltage, centrotemporal spikes, activated by ...