ARTHRITIS, SACROILIAC

General Information (adopted from Orphanet):

Synonyms, Signs:
Number of Symptoms 8
OrphanetNr:
OMIM Id: 108100
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0003401) Paresthesia 42 / 7739
2
(HPO:0012317) Sacroiliac arthritis 1 / 7739
3
(HPO:0000989) Pruritus 111 / 7739
4
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739
5
(OMIM) Sacroiliac pain, intermittent, severe 1 / 7739
6
(OMIM) Renal disease, uncharacterized (in some patients) 1 / 7739
7
(MedDRA:10042674) Swelling 3 / 7739
8
(OMIM) Elevated uric acid on urinalysis (in some patients) 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Clinical Description OMIM Stauffer and Merrihew (1944) reported a family segregating autosomal dominant sacroiliac arthritis, with 22 affected individuals over 4 generations. Affected individuals complained of episodes of pain beginning in the second decade of life, incapacitating in some patients, centered ...