ALOPECIA AREATA 1

General Information (adopted from Orphanet):

Synonyms, Signs: AU, INCLUDED
AA1 ALOPECIA UNIVERSALIS, INCLUDED
Number of Symptoms 6
OrphanetNr:
OMIM Id: 104000
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Multifactorial
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0002289) Alopecia universalis 20 / 7739
2
(HPO:0007418) Alopecia totalis 6 / 7739
3
(HPO:0001803) Nail pits 17 / 7739
4
(OMIM) Patchy round or oval hair loss (alopecia areata) 1 / 7739
5
(OMIM) Trachyonychia (rough surfaced nails) 1 / 7739
6
(OMIM) Peribulbar lymphocytic infiltrate (on scalp biopsy) 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Alopecia areata is a genetically determined, immune-mediated disorder of the hair follicle with an estimated lifetime risk of approximately 2%, making it one of the most common human autoimmune diseases (Gilhar and Kalish, 2006). It shows a spectrum ...
Clinical Description OMIM Alopecia areata is characterized by patchy hair loss on the scalp, which can eventually involve the entire scalp (alopecia totalis) or the entire body (alopecia universalis) (Martinez-Mir et al., 2007). The onset of the disease can be sudden, ...
Population genetics OMIM Among first-degree relatives of 348 severely affected patients, van der Steen et al. (1992) found that one of the parents was affected in 7%. Among the sibs, 3% had developed alopecia areata (AA), while AA was present in ...