ACTH-independent Cushing syndrome

General Information (adopted from Orphanet):

Synonyms, Signs: Adrenal Cushing syndrome
Corticotropin-independent Cushing syndrome
Adrenocorticotropic hormone-independent Cushing syndrome
Number of Symptoms 19
OrphanetNr: 99893
OMIM Id:
ICD-10: E24.8
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance:
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: Cushing syndrome
 -Rare endocrine disease

Symptom Information: Sort by abundance 

1
 (HPO:0000787) Nephrolithiasis Frequent [Orphanet] 78 / 7739
2
 (HPO:0000858) Menstrual irregularities Frequent [Orphanet] 42 / 7739
3
 (HPO:0000789) Infertility Frequent [Orphanet] 74 / 7739
4
 (HPO:0000311) Round face Very frequent [Orphanet] 104 / 7739
5
 (HPO:0100851) Abnormal emotion/affect behavior Frequent [Orphanet] 85 / 7739
6
 (HPO:0008221) Adrenal hyperplasia Very frequent [Orphanet] 24 / 7739
7
 (HPO:0000819) Diabetes mellitus Frequent [Orphanet] 131 / 7739
8
 (HPO:0001578) Hypercortisolism Very frequent [Orphanet] 17 / 7739
9
 (HPO:0100641) Neoplasm of the adrenal cortex Very frequent [Orphanet] 3 / 7739
10
 (HPO:0004325) Decreased body weight Very frequent [Orphanet] 492 / 7739
11
 (HPO:0001956) Truncal obesity Very frequent [Orphanet] 39 / 7739
12
 (HPO:0001061) Acne Frequent [Orphanet] 33 / 7739
13
 (HPO:0000978) Bruising susceptibility Frequent [Orphanet] 123 / 7739
14
 (HPO:0001065) Striae distensae Frequent [Orphanet] 26 / 7739
15
 (HPO:0000963) Thin skin Very frequent [Orphanet] 96 / 7739
16
 (HPO:0011362) Abnormal hair quantity Frequent [Orphanet] 92 / 7739
17
 (HPO:0000822) Hypertension Frequent [Orphanet] 224 / 7739
18
 (HPO:0002900) Hypokalemia Frequent [Orphanet] 45 / 7739
19
 (HPO:0001324) Muscle weakness Frequent [Orphanet] 859 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: