Familial gestational hyperthyroidism

General Information (adopted from Orphanet):

Synonyms, Signs:
Number of Symptoms 3
OrphanetNr: 99819
OMIM Id: 603373
ICD-10: E05.8
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: Genetic hypertension
 -Rare circulatory system disease
 -Rare genetic disease
 -Rare renal disease
Rare disorder related with pregnancy, childbirth and puerperium
 -Rare gynecologic or obstetric disease
Rare hyperthyroidism
 -Rare endocrine disease
 -Rare genetic disease

Symptom Information: Sort by abundance 

1
(HPO:0000836) Hyperthyroidism 9854118 IBIS 25 / 7739
2
(HPO:0012188) Hyperemesis gravidarum 9854118 IBIS 1 / 7739
3
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Some degree of stimulation of the thyroid gland by chorionic gonadotropin (see 118860) is common during early pregnancy. When serum chorionic gonadotropin concentrations are abnormally high, e.g., in women with molar pregnancies (231090), overt hyperthyroidism may ensue. The ...
Clinical Description OMIM Hyperemesis gravidarum is characterized by excessive vomiting in early pregnancy, leading to the loss of 5% or more of body weight. It is usually self-limited and therefore of little clinical consequence. Some women with the disorder have high ...