Transient erythroblastopenia of childhood

General Information (adopted from Orphanet):

Synonyms, Signs: ERYTHROBLASTOPENIA, TRANSIENT
TEC
Transient acquired pure red cell aplasia
Number of Symptoms 3
OrphanetNr: 98871
OMIM Id: 227050
ICD-10: D60.1
UMLs: C0238478
MeSH: C536980
MedDRA:
Snomed: 234375006

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal recessive inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: Red cell aplasia
 -Rare genetic disease
 -Rare hematologic disease

Symptom Information: Sort by abundance 

1
(HPO:0005510) Transient erythroblastopenia 1 / 7739
2
(HPO:0001903) Anemia 289 / 7739
3
(HPO:0000007) Autosomal recessive inheritance 2538 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Transient erythroblastopenia of childhood is a pure red cell aplasia that occurs in a previously healthy child, most commonly between 6 months and 4 years of age. The course is characterized by a complete recovery, usually within 1 ...
Clinical Description OMIM Seip (1982) observed transient erythroblastopenia in a brother and sister of unrelated parents. An age difference of 23 months separated the sibs. Onset was at 21 and 19 months, respectively, after an upper respiratory infection in the boy ...
Molecular genetics OMIM To determine if TEC and DBA are allelic, Gustavsson et al. (2002) investigated the segregation of markers spanning the RPS19 gene in 7 sib pairs with TEC. No structural mutations were identified.