Panhypopituitarism
General Information (adopted from Orphanet):
| Synonyms, Signs: |
|
| Number of Symptoms | 9 |
| OrphanetNr: | 90695 |
| OMIM Id: |
262600
312000 |
| ICD-10: |
E23.0 |
| UMLs: |
C0242343 |
| MeSH: |
|
| MedDRA: |
10033662 |
| Snomed: |
32390006 |
Prevalence, inheritance and age of onset:
| Prevalence: | No data available. |
| Inheritance: |
|
| Age of onset: |
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Disease classification (adopted from Orphanet):
| Parent Diseases: |
Hypogonadotropic hypogonadism associated with other endocrinopathies
-Rare endocrine disease -Rare genetic disease -Rare gynecologic or obstetric disease Nonacquired combined pituitary hormone deficiencies without extra-pituitary malformations -Rare endocrine disease -Rare genetic disease |
Symptom Information:
|
|
(HPO:0000135) | Hypogonadism | 89 / 7739 | ||||
|
|
(HPO:0002173) | Hypoglycemic seizures | 19 / 7739 | ||||
|
|
(HPO:0008202) | Prolactin deficiency | 3 / 7739 | ||||
|
|
(HPO:0000821) | Hypothyroidism | 141 / 7739 | ||||
|
|
(HPO:0000871) | Panhypopituitarism | 8 / 7739 | ||||
|
|
(HPO:0000846) | Adrenal insufficiency | 24 / 7739 | ||||
|
|
(HPO:0004322) | Short stature | 1232 / 7739 | ||||
|
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(HPO:0001998) | Neonatal hypoglycemia | 22 / 7739 | ||||
|
|
(HPO:0000007) | Autosomal recessive inheritance | 2538 / 7739 |
Associated genes:
ClinVar (via SNiPA)
| Gene symbol | Variation | Clinical significance | Reference |
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