Localized scleroderma

General Information (adopted from Orphanet):

Synonyms, Signs: Localized fibrosing scleroderma
Number of Symptoms 10
OrphanetNr: 90289
OMIM Id:
ICD-10: L94.0
UMLs: C0036420
MeSH: D012594
MedDRA: 10039712
Snomed: 201048007

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Not applicable
[Orphanet]
Age of onset: All ages
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Scleroderma
 -Rare skin disease

Symptom Information: Sort by abundance 

1
 (HPO:0001171) Split hand Occasional [Orphanet] 72 / 7739
2
 (HPO:0002817) Abnormality of the upper limb Occasional [Orphanet] 25 / 7739
3
 (HPO:0100559) Lower limb asymmetry Occasional [Orphanet] 30 / 7739
4
 (HPO:0010161) Abnormality of the phalanges of the toes Occasional [Orphanet] 3 / 7739
5
 (HPO:0100555) Asymmetric growth Occasional [Orphanet] 25 / 7739
6
 (HPO:0000951) Abnormality of the skin Very frequent [Orphanet] 147 / 7739
7
 (HPO:0000958) Dry skin Very frequent [Orphanet] 152 / 7739
8
 (HPO:0001053) Hypopigmented skin patches Very frequent [Orphanet] 80 / 7739
9
 (HPO:0003202) Skeletal muscle atrophy Frequent [Orphanet] 281 / 7739
10
 (OMIM) Stiff skin Very frequent [Orphanet] 31 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: