Fibronectin glomerulopathy

General Information (adopted from Orphanet):

Synonyms, Signs: GFND
Glomerulopathy with fibronectin deposits
Number of Symptoms 15
OrphanetNr: 84090
OMIM Id: 137950
601894
ICD-10: N07.6
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant
[Orphanet]
Age of onset: All ages
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Primary glomerular disease
 -Rare genetic disease
 -Rare renal disease

Symptom Information: Sort by abundance 

1
 (HPO:0100820) Glomerulopathy Very frequent [Orphanet] 46 / 7739
2
 (HPO:0000100) Nephrotic syndrome Very frequent [Orphanet] 83 / 7739
3
 (HPO:0011277) Abnormality of the urinary system physiology Very frequent [Orphanet] 5 / 7739
4
 (HPO:0003774) Stage 5 chronic kidney disease 78 / 7739
5
 (HPO:0000083) Renal insufficiency Very frequent [Orphanet] 232 / 7739
6
 (HPO:0002907) Microscopic hematuria 27 / 7739
7
 (HPO:0000112) Nephropathy 92 / 7739
8
 (HPO:0000093) Proteinuria Very frequent [Orphanet] 169 / 7739
9
 (HPO:0008636) Lobular glomerulopathy 1 / 7739
10
 (HPO:0000790) Hematuria Very frequent [Orphanet] 106 / 7739
11
 (HPO:0000822) Hypertension Very frequent [Orphanet] 224 / 7739
12
 (HPO:0002170) Intracranial hemorrhage Occasional [Orphanet] 40 / 7739
13
 (HPO:0010741) Edema of the lower limbs Very frequent [Orphanet] 34 / 7739
14
 (HPO:0000006) Autosomal dominant inheritance 2518 / 7739
15
 (HPO:0003677) Slow progression 134 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: